LMCB - MRC Laboratory for Molecular Cell Biology

15 July 2020

New publication in Nature Communications for de Bruin lab


In order for a cell to proliferate with fidelity, it must cycle through two non-overlapping events - replication of the genomic DNA during S phase and the segregation of the duplicated DNA into two genetically identical daughter cells during M phase. DNA replication is tightly regulated during S-phase. S-phase length is determined by DNA synthesis rate, but what controls or limits the DNA replic

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15 June 2020

New publication in Molecular Biology of the Cell for Pichaud Lab

journal cover

The shape of cells determines the shape and function of organs.  However, how cell shape is controlled is not well understood.

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05 June 2020

New publication in Current Biology for Baum and Henriques labs

Why try to image live cell divisions in the hyperthermophile Sulfolobus at 75°C? There are several reasons for wanting to do so. First, many cell biological processes previously thought to be unique to eukaryotes are present in a simplified form in TACK archaea (which include the archaeon Sulfolobus) – making this an excellent system in which to study how they work. This includes ESCRT-III and

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05 June 2020

Ready to open for UCL's return-to-work pilot

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20 May 2020

New publication in Molecular Biology of the Cell for Baum Lab

The ability of cells to divide along their longitudinal axis is thought to play a key role in maintaining epithelial tissue homeostasis. In a new publication in Molecular Biology of the Cell, Lam and colleagues find that in elongated cells, the ability for mitotic spindles to rotate to their correct orientation is dependent o

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19 May 2020

Natalie Kirkland on her recent publication in Current Biology

In a recent publication in Current Biology, the Mao Lab and colleagues investigated how changes in tissue architecture during growth influence mitotic nuclear migration.  We've asked Natalie Kirkland to tell us about the research.

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18 May 2020

MRC LMCB renews Athena SWAN Gold Award

Athena SWAN Gold Award

We are delighted to announce Athena SWAN has renewed our Gold Award, in recognition of our ongoing commitment to advancing equality, diversity and inclusion. We are the first department at UCL to renew a Gold Award and one of only 3 departments nationwide to be awarded Gold in this round of applications.

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14 May 2020

Yanlan Mao awarded Leverhulme Trust Project Grant

Yanlan Mao has been awarded a Leverhulme Trust Project Grant to investigate the role of the extracellular matrix in tissue morphogenesis. 

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13 May 2020

Alison Lloyd elected Fellow of the Academy of Medical Sciences

The Academy of Medical Sciences has elected 50 of the UK’s most prominent biomedical and health scientists to their Fellowship. We're proud to announce our Director, Alison Lloyd, has been chosen for her contributions to advancing biomedical science in the UK and beyond.

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08 April 2020

Taking cells back in time - new publication in eLife for Chubb lab

After damage to tissues, some cells are capable of reverting to a more embryo-like condition.  In this condition, they are then capable of growing to repair the damaged area and making different cell types to make sure the site becomes operational again.  This process of cells "going back in time" is called dedifferentiation but it is not well understood.

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