LMCB - MRC Laboratory for Molecular Cell Biology

19 December 2019

MRC LMB and Saiardi Lab collaborative paper published in Cell Reports

When infecting a cell, HIV appropriates some of the molecules in the cell for its own purposes.

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19 December 2019

New publication in Journal of Biological Chemistry for Saiardi Lab

In their recent publication in Journal of Biological Chemistry,  the Saiardi Lab build on their discovery of a novel post-translational modification of lysine residues in budding yeast, known as polyphosphorylation.

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09 December 2019

Yanlan Mao is awarded the first Early Career Award in Mechanobiology

Congratulations to Yanlan Mao! She has been selected as the winner of the first Early Career Award in Mechanobiology, awarded by the Biophysical Society.

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28 November 2019

New publication in Cell Reports for Acton Lab

Research abstract

Fibroblastic reticular cells control matrix production for lymph node conduit function. In a recent publication in Cell Reports, Martinez and colleagues show that matrix production is reduced and conduit flow is altered during lymph node expansion.

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26 November 2019

New publication in PNAS for Saiardi Lab

Research cartoon

Inositol phosphates are a class of small molecules involved in signalling and metabolism. The wide breadth of functions they are associated with, including cell migration, DNA repair, telomere length maintenance, insulin sensitivity, phosphate homeostasis, cell cycle regulation, and necroptosis, testifies to the importance of these molecules in biology.

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18 November 2019

A collaborative paper in Developmental Cell for the Stefan Lab

Research paper graphical abstract

Membrane contact sites (MCS) between the endoplasmic reticulum (ER) and the plasma membrane (PM) play fundamental roles in all eukaryotic cells.

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01 November 2019

New publication in ACS Chemical Biology for Saiardi Lab

Chemical reaction cartoon

Inositol and phosphate, can, in combination, produce a library of cell signaling molecules, simply referred as inositol phosphates. The fully phosphorylated inositol ring known as inositol hexakisphosphate (InsP6) controls various cellular functions directly or indirectly as precursors of inositol pyrophosphates such as InsP7 and InsP8.

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01 November 2019

Wellbeing at the LMCB

As part of the 2019 Wellbeing Month at UCL, we ran a taster PostureFit class open to all LMCB staff.

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01 November 2019

Melda Tozluoglu tells us about her recent publication in Dev Cell

Cartoon tissue folding

We've asked Melda Tozluoglu, from the Mao Lab, to tell us about her recent publication in Developmental Cell.

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28 October 2019

New publication by Baum and Saric Labs in BMC Biology

ESCRT-III is a ubiquitous biological nanomachine that reshapes and cuts cell membranes in a wide range of cellular processes, from vesicle formation, HIV and Ebola release, to cell division.

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