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New publication in Development for the Mao and Pichaud Labs
Building consensus on definition and nomenclature of HPB organoids
Hepatic, pancreatic and biliary (HPB) organoids have recently emerged as excellent model systems of regenerative processes and disease.
Collaborative publication in Cancer Discovery for de Bruin Lab
The de Bruin lab contributed to a new study from the Swanton lab, at the Francis Crick Institute, published in Cancer Discovery, i
Democratising deep learning for microscopy with ZeroCostDL4Mic
Deep Learning (DL) methods are increasingly recognised as powerful analysis tools for microscopy and can carry out many tasks like image segmentation, classification, object detection, denoising. Additionally, their potential to outperform conventional image processing pipelines is now well established.
New publication in J Biol Chem for the de Bruin Lab
A new study by the de Bruin lab, published in the Journal of Biological Chemistry, investigates how cells buffer transcription levels against changes in DNA copy number during S phase, known as gene expression homeostasis.
Review in Frontiers in Cell and Developmental Biology by Luigi Aloia
In a new review in Frontiers in Cell and Developmental Biology, Luigi Aloia examines the role of epigenetic regulation of cell-fate in determining adult liver regeneration after injury, and how the interplay between epigenetics and metabolism may contribute
New publication in Cell Reports for Riccio Lab
Neurons are one of the most specialised cell types in an organism. They have the main role of connecting to each other (eg. in our brain) or to other tissues (eg. our muscles). To reach their targets, neurons grow long cellular extensions, the dendrites and the axon, that have specific functions and rely on the expression of distinct proteins.
Review in Open Biology for Khalilgharibi and Mao
What role does the basement membrane of epithelial and endothelial tissues play in tissue development, homeostasis and disease?
Publication in Cardiology Research for Kriston-Vizi and Ketteler
A new study by Kalkhoran et al, published in Cardiology Research, shows hydralazine, a drug used to treat patients with hypertension and chronic heart failure, can reduce heart attack size and heart muscle cell death by inhibiting mitochondrial fission.
