EGA Institute for Women's Health


Maternal and Fetal Medicine

Maternal and Fetal Medicine research has a long established track record at UCL and includes the work of Professor Charles Rodeck, one of the pioneers of fetal medicine.

The Department, headed by Professor Simon Waddington, represents a significant collaboration of scientists and clinicians with a unifying aim to improve outcomes for pregnant women and their babies through improved diagnosis and treatment. Research ranges from investigation of mechanisms of conditions such as preterm birth, fetal growth restriction and perinatally acquired brain injury to the development of novel therapies using vector based gene delivery and stem cell based strategies to address prenatal acquired and congenital abnormalities.

Perinatal Brain

Perinatal Brain

Understanding the molecular signals triggered in the developing brain by damaging factors such as oxygen deprivation or infection is an important step in designing therapies to optimise neurological outcomes following preterm birth and labour complications.

maternal medicine

Maternal Medicine

A better understanding of the causes of pregnancy - related syndromes will lead to novel therapies that not only optimise pregnancy outcomes for mother and child, but also provides new opportunities for the primary prevention of future disease in mother, father and offspring in later life.

Gene Transfer Technology

Gene Transfer Technology

Latest developments in gene transfer technology are being used to develop perinatal gene therapy for early onset lethal genetic diseases as well as providing novel methods to understand fundamental cell signaling pathways and disease mechanism.

Prenatal Cell and Gene Therapy

Prenatal Cell and Gene Therapy

Current treatment options for fetuses identified as having congenital structural or genetic abnormalities are limited. Combining recent advances in stem cell and gene transfer technology with advanced bioengineering will enable fetal therapy earlier in pregnancy. 

Prenatal medicine

Centre for Prenatal Therapy

We aim to transform prenatal care by providing novel therapeutic options for parents whose unborn baby has a structural abnormality.

Preterm Birth

Preterm Labour

Understanding the complex interactions between maternal immune responses and resident bacterial populations (microbiome) provides new ways to predict the risk of preterm labour in early pregnancy as well as new therapeutic targets for prevention.

Thrombosis and Haemostasis

Thrombosis and Haemostasis

Research aimed to explore thrombosis and haemostasis issues in women and improve general and reproductive health of women affected with bleeding or thrombotic disorders in the UK and internationally.

Image for Cellular Reprogramming and Perinatal Cell Therapy Group

Cellular Reprogramming and Perinatal Therapy

We are a team of stem cell biologists working in regenerative medicine. We are passionate about improving the quality of life of children suffering from bone fragility or brain damage through the development of the next generation of innovative stem cell and cell-free therapeutics.

teaser image for Perinatal Care & Operative Birth Group

Perinatal Care & Operative Birth Group

Our research aim is to optimise health and safety in pregnancy and birth for every parent.  The group's work specifically focuses on birth and birth emergencies, as well as perinatal death and brain injury prevention.


Midwifery and Nursing Research

Our multidisciplinary research approach is focused on a number of particular areas. We are committed to improving the lives and experiences of women and their families. 

MFM Research Students

Current Research Students

Explore the list of research students within our Research Department of Maternal & Fetal Medicine and visit their profiles.