A better understanding of the causes of pregnancy - related syndromes will lead to novel therapies that not only optimise pregnancy outcomes for mother and child, but also provides new opportunities for the primary prevention of future disease in mother, father and offspring in later life.
Latest developments in gene transfer technology are being used to develop perinatal gene therapy for early onset lethal genetic diseases as well as providing novel methods to understand fundamental cell signaling pathways and disease mechanism.
Current treatment options for fetuses identified as having congenital structural or genetic abnormalities are limited. Combining recent advances in stem cell and gene transfer technology with advanced bioengineering will enable fetal therapy earlier in pregnancy.
We aim to transform prenatal care by providing novel therapeutic options for parents whose unborn baby has a structural abnormality.
Understanding the complex interactions between maternal immune responses and resident bacterial populations (microbiome) provides new ways to predict the risk of preterm labour in early pregnancy as well as new therapeutic targets for prevention.
Research aimed to explore thrombosis and haemostasis issues in women and improve general and reproductive health of women affected with bleeding or thrombotic disorders in the UK and internationally.
Fetal cells can be reprogrammed to become pluripotent, making them a valuable source of cells for perinatal therapy. Ongoing projects include the use of such cells to repair the developing brain following acute oxygen deprivation as well treating fetuses with brittle bone disease (osteogenesis imperfecta).
Our multidisciplinary research approach is focused on a number of particular areas. We are committed to improving the lives and experiences of women and their families.
Explore the list of research students within our Research Department of Maternal & Fetal Medicine and visit their profiles.