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Neurological Gene Annotation

The Neurological Gene Annotation project is focused on Gene Ontology (GO) annotation of neurological-relevant proteins. We contribute GO annotations for proteins to the GO Consortium, the attribution they are given is determined by the focus of the funded project. An example of a curated protein is human LRRK2.

Annotations contributed by this project to the GO Consortium dataset are attributed to ParkinsonsUK-UCL, ARUK-UCL or SynGO-UCL.

By using GO to curate the scientific literature we are creating a resource for the Parkinson’s, Alzheimer's and neurological research communities that will enable researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research.

See our latest news and progress in our current newsletter.

What we curate

Current Projects

  • Alzheimer's Research UK-funded GO annotation initiatives:

    • Neurological processes involving tau and its interacting partners
    • Proteins involved in neuroinflammation
  • SynGO project: an international collaborative effort to annotate synaptic proteins

Completed Projects

  • Alzheimer's Research UK-funded GO annotation initiatives to annotate amyloid-beta binding proteins
  • Parkinson's UK-funded GO annotation initiative to annotate processes relevant to Parkinson's disease

Contribute

You can contribute by

  • reviewing the annotation of your favourite gene and telling us what's missing or inaccurate (or tell us if we've done a good job!)
  • suggesting papers for curation
  • Contact Us