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Full details of the grant holders, biocurators, editors, software engineers and scientific advisors involved in various projects are listed below, along with supporting societies and groups.

The UCL annotation team is based in the Research Department of Preclinical and Fundamental Science and within the UCL Institute of Cardiovascular Sciences (ICS).  We are reliant on our collaborations, both within UCL, at other universities and at EMBL-EBI, as well as our membership of the Gene Ontology and International Molecular Exchange Consortiums.

    2019-2020 Regulation of Interleukins by miRNAs

    Grant holders

    Biocurator

    2018-2019 Alzheimer's Research UK grant NSG2018-003

    Co-grant holders

    Biocurators

    2017-2020 Alzheimer's Research UK grant NAS2017A-1

    Co-grant holders

    Biocurators

    EMBL-EBI staff

    2017 Alzheimer's Research UK grant NSG2016-13

    Co-grant holders

    Biocurator

    2013-2018 British Heart Foundation RG/13/5/30112

    Co-grant holders

    Biocurators

    EMBL-EBI staff

    2014-2016 Parkinson's UK grant G-1307

    Co-grant holders

    Biocurators

    EMBL-EBI staff

      2007-2012 British Heart Foundation SP/07/007/23671

      Co-grant holders 

      Biocurators

      EMBL-EBI staff

      Neurological International Scientific Advisory Panel
      • Professor John Hardy - Chair of Molecular Biology of Neurological Disease at the UCL Institute of Neurology
      • Professor Tracy Hussell - Director of the Manchester Collaborative Centre for Inflammation Research, University of Manchester
      • Dr Jo Knight - Lancaster University Medical School and Data Science Institute (2017-2019)
      • Professor Paul Whiting - Chief Scientific Officer of the Alzheimer's Research UK UCL Drug Discovery Institute
      • Elizabeth Wu - Director of Innovation Development - Alzforum 
      • Dr Dervis Salih - Department of Neurodegenerative Diseases at UCL Queen Square Institute of Neurology
      • Dr Jennifer Pocock - Department of Neuroinflammation at UCL Queen Square Institute of Neurology
      Cardiovascular International Scientific Advisory Panel
      2004-2007 Wellcome Trust: HUGO Gene Nomenclature Committee (HGNC) HUGOA

      Grant holder

      Biocurators

      Additional project-specific advisors
      NameTopic
      Professor Steve HumphriesLipid metabolism
      Professor Philippa TalmudLipid metabolism
      Dr Ross BreckenridgeHeart development
      Cardiac conduction
      Professor Shoumo BhattarcharyaHeart development
      Professor Paul RileyHeart development
      Cardiac conduction
      Professor Peter ScamblerHeart development
      Dr Andrea Townsend-NicholsonSignalling
      Professor Lucie ClappCardiac conduction
      Dr Perry ElliotCardiac conduction
      Dr Pier LambiaseCardiac conduction
      Dr Andy TinkerCardiac conduction
      Dr Claudia ManzoniParkinson's disease
      Professor Manuel MayrmicroRNAs
      Dr. Anna ZampetakimicroRNAs
      Dr. Lars MaegdefesselmicroRNAs
      Dr. Anastasia KaleamicroRNAs
        Postgraduate Students

        PhD student

        • 2018 - 2019: Saadullah Ahmad, Thesis title Aortic Valve Stenosis: An Understanding of the Disease Process from Fetus to Adult and Insights into its Treament

        MSc Students

        As part of the UCL Genetics Institute's MSc in Genetics of Human Disease, students are required to complete a project consisting of an original piece of research. The Functional Gene Annotation Team offer bioinformatics-based projects that provide MSc and iBSc students with experience in a variety of bioinformatic resources. In addition, the students contribute valuable GO annotations.

          Annotation Volunteers

          Having attended our Bioinformatics and Gene Ontology Annotation Workshop, the following attendees decided to continue to submit annotations to the GO database:

          • Andrea Townsend-Nicholson (UCL)
          • Mathew Tata (UCL)
          • Jonathan Watkins (Birkbeck College)
          • Raffaele Ferrari (UCL)
          • David Gregory (UCL)
          • Helen Jones (UCL)
          • Janos Kriston-Vizi (UCL)
          • Thokchom Lellel (MIzoram University, India)

          You can contribute by:

          • Reviewing the annotation of your favourite gene and telling us what's missing or inaccurate (or tell us if we've done a good job!)
          • Suggesting papers for curation.

          Please email us: r.lovering@ucl.ac.uk. Alternatively you can contribute to GO by following the instructions on the GO Consortium or the EBI websites.

           

           

          Supporting Societies and Groups

          We are thankful to the following learned societies and academic groups for their support of the Functional Gene Annotation effort.

          Societies and Groups

          Journals

          Previous Supporters

          • ITMAT/Broad/CARE Consortia
          • HUPO Cardiovascular Initiative
          • UK Affymetrix

          The Functional Gene Annotation team is supported by Alzheimer's Research UK grant ARUK-NAS2017A-1 and the National Institute for Health Research University College London Hospitals Biomedical Research Centre.

          ARUK Campaign

          EMBL-EBI logo
          Manchester
          Gene Annotation Logo
          RNA
          UniProt logo
          IntAct Logo
          IMEx logo

           

           

          Contact Us

          Highlights

          Ruth Lovering Resignation

          Although I resigned at the end of August 2023, I am still working through the GO annotations that need to be revised (due to a change in the GO Consortium guidelines). In addition, I have been invited to provide a few lectures at UCL and I have a few papers to complete. Thank you again to the British Heart Foundation, Alzheimer Research UK and Parkinson's UK for their funding and thank you to all of the scientists and members of the GO consortium that have collaborated with the Functional Annotation team. Most importantly, thank you to all the biocurators who joined the team, you were a pleasure to work with and made an amazing impact on the GO annotation of human gene products.

          Recent Publications

          • Luna Buitrago, D.; Lovering, R.C.; Caporali, A. Insights into Online microRNA Bioinformatics Tools. Non-Coding RNA2023, 9, 18.
          • Lovering RC, Gaudet P, Acencio ML, Ignatchenko A, Jolma A, Fornes O, Kuiper M, Kulakovskiy IV, Lægreid A, Martin MJ, Logie C. A GO catalogue of human DNA-binding transcription factors. Biochim Biophys Acta Gene Regul Mech. 2021 1864(11-12):194765. PMID: 34673265.

          Contact details

          Rayne Building, 5 University Street, London. WC1E 6JF

          Professor Ruth Lovering r.lovering@ucl.ac.uk
          URL: www.ucl.ac.uk/functional-gene-annotation