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Functional Gene Annotation
Lead: Professor Ruth Lovering
Group Members: Dr Barbara Kramarz
We curate the scientific literature to provide;
Gene Ontology (GO) annotations to the GO Consortium
Protein interaction data to the IMEx Consortium
The gene product functional information we provide enables researchers to rapidly evaluate and interpret data and generate hypotheses to guide future research into cardiovascular and neurological processes and disease. To date the annotation team at UCL has provided 10% of the manual GO annotations associated with human gene products, and contributed to the creation of almost 3000 new GO terms. We are currently funded by Alzheimer's Research UK and we have previously been funded by the British Heart Foundation and Parkinson's UK to annotate proteins and microRNAs.
