UCL Chemistry NMR Instruments


TCI and TXO Cryoprobes in Leeds, 950 MHz

Dr Arnout P. Kalverda, Website

Astbury BioStructure Laboratory Faculty of Biological Sciences, School of Chemistry
University of Leeds, Leeds, LS2 9JT

Instrument: Bruker 950 MHz Aeon NMR system currently with a TCI cryoprobe featuring cooled preamplifiers on Proton, Carbon, Nitrogen and Deuterium and with a dual receiver setup. New cryoprobes will arrive at the start of 2017 consisting of a TXO optimised for Nitrogen and Carbon direct detection and a 3mm TCI for highest mass sensitivity on proteins. Highest field available in the UK (together with the MRC NMR facility at the Francis Crick Institute), highest field for direct Carbon and Nitrogen detection. Most sensitive system in the world for direct Nitrogen detection (from early 2017). First 3mm triple resonance probe above 800 MHz (from early 2017). These features can be combined with dual receiver technology for simultaneous detection of multiple nuclei.

Unusual feature: High field, direct carbon and nitrogen detection, dual receivers, 3mm cryoprobe

1H Frequency: 950 MHz

Console, age: Bruker Avance III HD, 6 months

Probes, nuclei, gradients, age:

     5 mm TCI cryoprobe (until 2017), 1H, 13C, 15N, z-gradients, 2 years

     3 mm TCI cryoprobe (from 2017)  1H, 13C, 15N, z-gradients

     5 mm TXO cryoprobe (from 2017) 15N, 13C, 1H, z-gradients

Temperature range: -40 - 80 oC

Approximate proportion for shared usage: 20%

Staff availability for sample preparations: No