UCL Queen Square Institute of Neurology


Division of Neuropathology

The Division of Neuropathology at Queen Square is a leading academic and diagnostic neuropathology department in the UK. The department provides services for the National Hospital of Neurology and Neurosurgery, University College London Hospital, and receives a substantial number of national referrals.

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Molecular Pathology: We offer DNA methylation profiling for advanced diagnostics and prognostication of brain tumours.

For routine diagnostics we offer targeted sequencing (IDH, BRAF, TERT, Histone), copy number assays 1p/19q, EGFR, CDKN2A/B) and MGMT promoter methylation

Adult Muscle and Nerve: We receive more than 150 muscle and 100 nerve biopsies annually from adult patients and provide a diagnostic service and support the mitochondrial disease and the McArdle’s disease NCG services.
Dubowitz Neuromuscular Centre: The Dubowitz Neuromuscular centre specialises in neuromuscular disorders affecting individuals in the paediatric age. We provide the diagnostic neuropathology for Congenital Muscular Dystrophies and Congenital Myopathies
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Brain autopsies:
We perform autopsies on brains including high risk (prion diseases, Creutzfeldt-Jakob disease).
Enquiries: UCLH.office.neuropathology@nhs.net
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UCL IQPath: Research histology facility, digital pathology and image analysis on the highest technical level.
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Electron microscopy:

Comprehensive facilities for specimen preparation and access to Transmission Electron Microscopes at Great Ormond Street Hospitals. We provide diagnostic services only

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