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Biomaterials and Surgical Reconstruction
Our work
As a multidisciplinary team of academics (cell biologists, chemists, and material scientists) and clinicians, we deliver clinical solutions by innovating new biomaterials, scaffolds, and devices.
Our facilities
We have state-of-the-art facilities for synthesis, process, and physico-chemical and biological characterisation and imaging. These include an imaging suite containing TEM, SEM, AFM, confocal and 3D microscopy, a polymer chemistry laboratory and biomanufacturing laboratory equipped with commercial and custom-made 3D printers and bioprinters, electrospinning / electro-spraying equipment, and vascular graft coagulation extrusion housed within a GMP/GLP environment.
Centre for Biomaterials in Surgical Reconstruction and Regeneration (CBSRR)
Academic staff
Head: Prof. Wenhui Song
Deputy Head: Prof. Janice Tsui
Research fellows and assistants
Honorary staff
Dr Michelle Griffin
Mr Chung Lim
Dr Shao-An Xue
Prof. Xuetong Zhang (Newton Fellow)
Funding / Partnerships
There are several on-going projects in different stages of clinical and preclinical studies. These include cardiovascular grafts and stents, soft tubular organs, muscle, artificial cornea, cartilage and bone tissue engineering, chronic wound healing materials, artificial cochlea, breast implants, maxillofacial implants and light responsive soft robotics.
Funding is provided by the Wellcome Trust, EPSRC, BBSRC, MRC, Royal Society, Bone Cancer Research Trust, Osteoarthritis UK, British Heart Foundation, Royal Free Charity and industry.
Select publications
- Song, W. (2022). A smart sensor that can be woven into everyday life. Nature, 603, 585-586.
- Cheesbrough, A., Sciscione, F., Darbyshire, A., Song, W., et al. (2022). Biobased Elastomer Nanofibers Guide Light‐Controlled Human‐iPSC‐Derived Skeletal Myofibers. Advanced Materials, 34 (18), 2110441.
- Rezaei, A., Li, Y., Turmaine, M., Bertazzo, S., Jell, G., et al. (2022). Hypoxia mimetics restore bone biomineralisation in hyperglycaemic environments. Scientific Reports, 12 (1), 13944.
- Georgi, M., Morka, N., Patel, S., Kazzazi, D., Tsui, J., et al. (2022). The Impact of Same Gender Speed-Mentoring on Women's Perceptions of a Career in Surgery - A Prospective Cohort Study. Journal of Surgical Education.
- Zhu, G. H., Azharuddin, M., Islam, R., Patra, H.K., et al. (2021). Innate Immune Invisible Ultrasmall Gold Nanoparticles-Framework for Synthesis and Evaluation. ACS Applied Materials and Interfaces.
- Viola, G., Chang, J., Maltby, T., Steckler, F., Song, W., et al. (2020). Bio-inspired multi-resonant acoustic devices based on electrospun piezoelectric polymeric nanofibres. ACS Appl Mater Interfaces.
- Li, G., Hong, G., Dong, D., Song, W., & Zhang, X. (2018). Multi-responsive Graphene Aerogel-directed Phase Change Smart Fibres. Advanced Materials.
- Wu, L., Liu, C., Darbyshire, A., Loizidou, M., Emberton, M., Song, W., et al. (2018). Stiffness memory of indirectly 3D-printed elastomer nanohybrid regulates, chondrogenesis and osteogenesis of human mesenchymal stem cells. Biomaterials, Vol. 186, Dec. 64-79.
