UCL Division of Surgery and Interventional Science


Biomaterials and Surgical Reconstruction

Our internationally renowned Centre for Biomaterials in Surgical Reconstruction and Regeneration (CBSRR) develops innovative materials that address real medical needs.

Our work

As a multidisciplinary team of academics (cell biologists, chemists, and material scientists) and clinicians, we deliver clinical solutions by innovating new biomaterials, scaffolds, and devices.

Our strengths

  • Synthesis and characterisation of novel polymers, polymer composites, nanomaterials, and nanocomposites.
  • Design, manufacture and characterisation of implants, scaffolds, nano-vehicles for drug delivery and devices.
  • Biofunctionalization and modifying the physicochemical properties of materials to direct desirable biological interactions.

Our research areas include

  • Biomaterials and Nanocomposites
  • Tissue Engineering and Synthetic Tissues/Organs
  • Interface between Scaffolds and Cells
  • Implantable Electronics and Devices
  • Biomanufacturing

Our facilities

We have state-of-the-art facilities for synthesis, process, and physico-chemical and biological characterisation and imaging. These include an imaging suite containing TEM, SEM, AFM, confocal and 3D microscopy, a polymer chemistry laboratory and biomanufacturing laboratory equipped with commercial and custom-made 3D printers and bioprinters, electrospinning / electro-spraying equipment, and vascular graft coagulation extrusion housed within a GMP/GLP environment.

Access our facilities 

Centre for Biomaterials in Surgical Reconstruction and Regeneration (CBSRR)

Academic staff

Wenhui Song

Head: Prof. Wenhui Song

Janice Tsui

Deputy Head: Prof. Janice Tsui

Gavin Jell

Prof. Gavin Jell

Dr Hirak Patra

Dr Hirak Patra

George Hamilton

Prof. George Hamilton

Peter Butler

Prof. Peter Butler

Ash Mosahebi

Prof. Afshin (Ash) Mosahebi

Kaveh Shakib

Prof. Kaveh Shakib

Research fellows and assistants

Dr Jinke Chang

Dr Jinke Chang

Dr Alexandru Chivu

Dr Alexandru Chivu

Dr Xia Huang

Dr Xia Huang

Dr Azadeh Razaei

Dr Azadeh Razaei

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Thomas Lester

Honorary staff

Mr Daryll Baker

Mr Daryll Baker

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Dr Michelle Griffin

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Mr Chung Lim

Nima Naderi

Miss Nima Naderi

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Dr Shao-An Xue

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Prof. Xuetong Zhang (Newton Fellow)

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Funding / Partnerships

There are several on-going projects in different stages of clinical and preclinical studies. These include cardiovascular grafts and stents, soft tubular organs, muscle, artificial cornea, cartilage and bone tissue engineering, chronic wound healing materials, artificial cochlea, breast implants, maxillofacial implants and light responsive soft robotics.

Funding is provided by the Wellcome Trust, EPSRC, BBSRC, MRC, Royal Society, Bone Cancer Research Trust, Osteoarthritis UK, British Heart Foundation, Royal Free Charity and industry.

Select publications

  1. Song, W. (2022). A smart sensor that can be woven into everyday life. Nature, 603, 585-586.
  2. Cheesbrough, A., Sciscione, F., Darbyshire, A., Song, W., et al. (2022). Biobased Elastomer Nanofibers Guide Light‐Controlled Human‐iPSC‐Derived Skeletal Myofibers. Advanced Materials, 34 (18), 2110441.
  3. Rezaei, A., Li, Y., Turmaine, M., Bertazzo, S., Jell, G., et al. (2022). Hypoxia mimetics restore bone biomineralisation in hyperglycaemic environments. Scientific Reports, 12 (1), 13944.
  4. Georgi, M., Morka, N., Patel, S., Kazzazi, D., Tsui, J., et al. (2022). The Impact of Same Gender Speed-Mentoring on Women's Perceptions of a Career in Surgery - A Prospective Cohort Study. Journal of Surgical Education.
  1. Zhu, G. H., Azharuddin, M., Islam, R., Patra, H.K., et al. (2021). Innate Immune Invisible Ultrasmall Gold Nanoparticles-Framework for Synthesis and Evaluation. ACS Applied Materials and Interfaces.
  2. Viola, G., Chang, J., Maltby, T., Steckler, F., Song, W., et al. (2020). Bio-inspired multi-resonant acoustic devices based on electrospun piezoelectric polymeric nanofibres. ACS Appl Mater Interfaces.
  3. Li, G., Hong, G., Dong, D., Song, W., & Zhang, X. (2018). Multi-responsive Graphene Aerogel-directed Phase Change Smart Fibres. Advanced Materials.
  4. Wu, L., Liu, C., Darbyshire, A., Loizidou, M., Emberton, M., Song, W., et al. (2018). Stiffness memory of indirectly 3D-printed elastomer nanohybrid regulates, chondrogenesis and osteogenesis of human mesenchymal stem cells. Biomaterials, Vol. 186, Dec. 64-79.

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