UCL Division of Surgery and Interventional Science

Mr Reza Motallebzadeh

Mr Reza Motallebzadeh

Clinical Senior Lecturer in Renal Transplant Surgery and Honorary

Department of Surgical Biotechnology

Div of Surgery & Interventional Sci

Joined UCL
4th Sep 2017

Research summary

Reza Motallebzadeh directs the basic science and translational academic research from the Transplant Directorate at the Royal Free Hospital and Institute of Immunity and Transplantation, and leads the unit’s clinical renal transplantation trials portfolio.  


Reza's laboratory is focused on collaborative, multidisciplinary and translational research in experimental and clinical kidney transplantation. The research themes are underpinned by a commitment to developing innovative collaborations with academic centres and industrial partners to address fundamental questions concerning end-stage kidney disease and kidney transplantation. Reza's clinical research programme similarly utilises a multidisciplinary approach to address key clinical challenges in kidney transplantation and vascular access surgery. These include -


- Understanding the immune mechanisms underlying development of allograft vasculopathy and chronic rejection in solid organ transplantation, in particular the role of T follicular helper cells.


 - Development of biomarkers for acute and chronic allograft rejection.  


 - Delineating the role of the microbiota in renal transplantation.


 - Developing 3D culture models of renal fibrosis using organoids based on human kidney extracellular matrix scaffolds.

Teaching summary

1. Lead for the UCL MB PhD programme

2. Co-module Lead & Course Tutor for the Transplantation Science module of the MSc/MRes Programme in Human Tissue Repair and Surgical and Interventional Sciences (SURG0083: Transplantation Science). 


3. Module Lead & Course Tutor for the Student Selected Component in Transplantation Sciences (MBBS Year 2 SSC: Transplantation Sciences, SSC110).


4. Teaching of undergraduate and postgraduate medical students, UCL


5. Clinical Supervisor for surgical trainees in renal transplantation.


Royal College of Surgeons of England
Doctorate, Fellow Of The Royal College Of Surgeons | 2015
University of Cambridge
Doctorate, Doctor of Philosophy | 2012
St George's Hospital Medical School
Doctorate, Doctor of Medicine | 2006
University of Cambridge
Other higher degree, Master of Arts | 2000
University of Cambridge
Doctorate, Bachelor of Medicine/ Bachelor of Surgery | 1998
University of Cambridge
First Degree, Bachelor of Arts | 1996


Reza Motallebzadeh was educated at Westminster School, London and completed the pre-clinical and clinical Medical Sciences Tripos at St. John's College, University of Cambridge. Reza initially trained as a specialist registrar in cardiothoracic surgeon in London, and undertook a research MD at St. George’s Hospital, London University. Reza was always fascinated by immunology and subsequently pursued a career in abdominal transplantation surgery. He completed a PhD (2008-2011) in the Department of Surgery, University of Cambridge, to understand the role of tertiary lymphoid organs in chronic allograft rejection, and then, as a NIHR Academic Clinical Lecturer, his work focused on the role of germinal centre B cells in alloantibody-mediated rejection. 


Reza joined the Royal Free London NHS Trust as Honorary Consultant Renal Transplant Surgeon and Associate Professor, University College London in September 2017. He is Head of Centre for Transplantation in the Department of Renal Medicine, and Deputy Head, Centre for Surgical Innovation, Organ Repair and Transplantation, Division of Surgery and Interventional Science, UCL.