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UCL Queen Square Institute of Neurology

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Queen Square Multiple Sclerosis Centre

The Centre unites multiple sclerosis (MS) research and care at the UCL Queen Square Institute of Neurology and UCLH National Hospital for Neurology and Neurosurgery in central London, and has links across UCL.

Vision statement

Our activities are broad and aim to:
1.    Understand the disease mechanisms underlying clinical progression through the development and use of accurate laboratory models of MS, and fluid biomarker and magnetic resonance imaging (MRI) studies.
2.    Identify new treatment strategies able to slow or prevent demyelination and neurodegeneration, and promote tissue repair, in all clinical types of MS.
3.    Develop MRI techniques to aid in the accurate and timely diagnosis of MS, understand MS pathophysiology, predict clinical outcomes, and sensitively detect treatment effects in early studies of new treatments.
4.    Develop new clinical trial designs and analysis strategies to accelerate the testing of new medicines.
5.    Improve patient support, symptomatic treatment and rehabilitation, in order to reduce disability and improve well-being.
6.    Build expertise in MS research by supporting and mentoring early career investigators.
7.    Develop clinical practice through education and training opportunities for healthcare professionals in primary and secondary care.

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MS Laboratory Research

A wide range of techniques and expertise is applied to understanding the mechanisms responsible for MS, and developing new therapeutic strategies.

Brain areas with the strongest link between grey matter loss and risk of disability accumulation, with the thalamus shown in yellow

MS Clinical Research

The Queen Square Multiple Sclerosis Centre unites research expertise and care in MS that exists at the UCL Queen Square Institute of Neurology and the UCLH National Hospital for Neurology and Neurosurgery, Queen Square, in Central London. In addition the Centre links the wide variety of MS research across the different sites of UCL.

MS PATIENT REFLEX TEST

MS Clinical Trials

Clinical Trials on new therapies for MS are based at the National Hospital for Neurology and Neurosurgery (NHNN) and the Leonard Wolfson Experimental Neurology Centre (LWENC) based in Queen Square.

For-Patients-NHNN

MS Clinical Services

At the National Hospital for Neurology and Neurosurgery (NHNN) based in Queen Square a multidisciplinary team offers a wide range of expert specialist advice on all aspects of multiple sclerosis (MS), and carry out clinical research projects.

Trial updates