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The Facility Publications

 

  1. Phytosterols in human serum as measured using a liquid chromatography tandem mass spectrometry, Marie Claire GielenYu Chun TengNina M De GruijterCoziana CiurtinElizabeth C RosserKersti Karu, ChemRxiv, 4 Dec 2023, https://chemrxiv.org/engage/chemrxiv/article-details/656c38e6cf8b3c3cd7a...
  2. Antibiotic Residues in UK Foods: Exploring the Exposure Pathways and Associated Health Risks, Jegak Seo, Frank Kloprogge, Andrew M Smith, Kersti Karu, Lena Ciric, in publication, Toxics, Feb 2024.
  3. Two-substrate enzyme engineering using small libraries that combine the substrate preferences from two different variant lineages. Mukhopadhyay A, Karu K, Dalby PA.Sci Rep. 2024 Jan 14;14(1):1287. doi: 10.1038/s41598-024-51831-z.PMID: 38218974 
  1. The Nitrile Bis-Thiol Bioconjugation Reaction. Patel M, Forte N, Bishop CR, Porter MJ, Dagwell M, Karu K, Chudasama V, Baker JR.J Am Chem Soc. 2024 Jan 10;146(1):274-280. doi: 10.1021/jacs.3c08762. Epub 2023 Dec 20.PMID: 38124442 
  1. Antibiotic resistance genes and the association with bacterial community in biofilms occurring during the drinking water granular activated carbon (GAC) sandwich biofiltration. Xu L, Canales M, Zhou Q, Karu K, Zhou X, Su J, Campos LC, Ciric L.J Hazard Mater. 2023 Oct 15;460:132511. doi: 10.1016/j.jhazmat.2023.132511. Epub 2023 Sep 9.PMID: 37708648 
  1. Antibacterial Properties of Honey Nanocomposite Fibrous Meshes. Matharu RK, Ahmed J, Seo J, Karu K, Golshan MA, Edirisinghe M, Ciric L.Polymers (Basel). 2022 Nov 27;14(23):5155. doi: 10.3390/polym14235155.PMID: 36501550 
  1. Unearthing the unique stability of thiophosphonium-C-terminal cysteine adducts on peptides and proteins. Spears RJ, Chrzastek A, Yap SY, Karu K, Aliev AE, Baker JR, Chudasama V.Chem Commun (Camb). 2022 Apr 28;58(35):5359-5362. doi: 10.1039/d2cc01090a.PMID: 35394478
  1. Identification of diverse lipid-binding modes in the groove of zinc α2 glycoprotein reveals its functional versatility. Zahid H, Lau AM, Kelly SM, Karu K, Gor J, Perkins SJ, McDermott LC.FEBS J. 2022 Apr;289(7):1876-1896. doi: 10.1111/febs.16293. Epub 2021 Dec 7.PMID: 34817923 
  1. Probing cytochrome P450 (CYP) bioactivation with chloromethylindoline bioprecursors derived from the duocarmycin family of compounds. Ortuzar N, Karu K, Presa D, Morais GR, Sheldrake HM, Shnyder SD, Barnieh FM, Loadman PM, Patterson LH, Pors K, Searcey M.Bioorg Med Chem. 2021 Jun 15;40:116167. doi: 10.1016/j.bmc.2021.116167. Epub 2021 Apr 21.PMID: 33932713
  1. Correction: Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis. Morais M, Nunes JPM, Karu K, Forte N, Benni I, Smith MEB, Caddick S, Chudasama V, Baker JR.Org Biomol Chem. 2021 Apr 7;19(13):3024. doi: 10.1039/d1ob90035h. Epub 2021 Mar 24.PMID: 33885556
  1. Simultaneous measurement of free and conjugated estrogens in surface water using capillary liquid chromatography tandem mass spectrometry. Huang F, Karu K, Campos LC.Analyst. 2021 Apr 26;146(8):2689-2704. doi: 10.1039/d0an02335c.PMID: 33751008
  1. Removal of antibiotics in sand, GAC, GAC sandwich and anthracite/sand biofiltration systems. Xu L, Campos LC, Li J, Karu K, Ciric L.Chemosphere. 2021 Jul;275:130004. doi: 10.1016/j.chemosphere.2021.130004. Epub 2021 Feb 17.PMID: 33640744
  1. Continuous Single-Phase Synthesis of [Au25(Cys)18] Nanoclusters and their Photobactericidal Enhancement. Hwang GB, Wu G, Shin J, Panariello L, Sebastian V, Karu K, Allan E, Gavriilidis A, Parkin IP.ACS Appl Mater Interfaces. 2020 Oct 28;12(43):49021-49029. doi: 10.1021/acsami.0c07691. Epub 2020 Oct 19.PMID: 33073567
  1. Cysteine-to-lysine transfer antibody fragment conjugation.Forte N, Benni I, Karu K, Chudasama V, Baker JR.Chem Sci. 2019 Oct 11;10(47):10919-10924. doi: 10.1039/c9sc03825f. eCollection 2019 Dec 21.PMID: 32190247 Free PMC article.
  1. Photobactericidal activity activated by thiolated gold nanoclusters at low flux levels of white light. Hwang GB, Huang H, Wu G, Shin J, Kafizas A, Karu K, Toit HD, Alotaibi AM, Mohammad-Hadi L, Allan E, MacRobert AJ, Gavriilidis A, Parkin IP.Nat Commun. 2020 Mar 5;11(1):1207. doi: 10.1038/s41467-020-15004-6.PMID: 32139700 Free
  1. Quantitative Proteomic Analysis of the Central Amygdala in Neuropathic Pain Model Rats.Karu K, Swanwick RS, Novejarque-Gadea A, Antunes-Martins A, Thomas B, Yoshimi E, Foster W, Fang M, McMahon SB, Bennett DLH, Rice ASC, Okuse K.J Proteome Res. 2020 Apr 3;19(4):1592-1619. doi: 10.1021/acs.jproteome.9b00805. Epub 2020 Mar 3.PMID: 32050077
  1. Optimised approach to albumin-drug conjugates using monobromomaleimide-C-2 linkers. Wall A, Nicholls K, Caspersen MB, Skrivergaard S, Howard KA, Karu K, Chudasama V, Baker JR.Org Biomol Chem. 2019 Aug 28;17(34):7870-7873. doi: 10.1039/c9ob00721k.PMID: 31410415
  1. LC-MS analysis to determine the biodistribution of a polymer coated ilomastat ocular implant. Mohamed-Ahmed AHA, Lockwood A, Fadda H, Madaan S, Khaw PT, Brocchini S, Karu K.J Pharm Biomed Anal. 2018 Aug 5;157:100-106. doi: 10.1016/j.jpba.2018.05.017. Epub 2018 May 17.PMID: 29777984
  1. Effect of Flavin-Containing Monooxygenase Genotype, Mouse Strain, and Gender on Trimethylamine N-oxide Production, Plasma Cholesterol Concentration, and an Index of Atherosclerosis. Veeravalli S, Karu K, Scott F, Fennema D, Phillips IR, Shephard EA.Drug Metab Dispos. 2018 Jan;46(1):20-25. doi: 10.1124/dmd.117.077636. Epub 2017 Oct 25.PMID: 29070510 Free PMC article.
  1. A highly sensitive liquid chromatography electrospray ionization mass spectrometry method for quantification of TMA, TMAO and creatinine in mouse urine. Veeravalli S, Karu K, Phillips IR, Shephard EA.MethodsX. 2017 Sep 28;4:310-319. doi: 10.1016/j.mex.2017.09.004. eCollection 2017.PMID: 29062719 Free PMC article.
  1. Optimisation of the dibromomaleimide (DBM) platform for native antibody conjugation by accelerated post-conjugation hydrolysis. Morais M, Nunes JPM, Karu K, Forte N, Benni I, Smith MEB, Caddick S, Chudasama V, Baker JR.Org Biomol Chem. 2017 Apr 5;15(14):2947-2952. doi: 10.1039/c7ob00220c.PMID: 28290574
  1. Influence of PPCPs on the performance of intermittently operated slow sand filters for household water purification. Pompei CME, Ciric L, Canales M, Karu K, Vieira EM, Campos LC.Sci Total Environ. 2017 Mar 1;581-582:174-185. doi: 10.1016/j.scitotenv.2016.12.091. Epub 2016 Dec 29.PMID: 28041695