Presentation at Annual Conference on Brain Disorders, Neurology and Therapeutics, Paris, October 201

The presentation highlighted the aim to understand the role of the alternative pathway of the complement system in neonatal hypoxia-ischemia brain damage.  Using knock out mice they found that the activation of the alternative pathway increases the damage in the HI brain.

They are now planning to test a pharmaceutical compound to inhibit this pathway chemically and have a neuroprotective effect. This is groundbreaking research as no one has looked at this pathway in neonatal HI before and seen the current lack of effective treatments for this disease we might give hope to families with babies born with such disease.