Wolfson Institute for Biomedical Research



Availability: Full-time 1 year


Students undertake modules to the value of 180 credits. The programme consists of five taught modules (75 credits), and a research/dissertation (105 credits).

Complusory Modules 

MEDC0049: Ethics and Regulation of Research (Term 1, 15 credits)

MEDC0084: Research project (105 credits - start January).

Optional Modules

Students will select four from the following modules (15 credits each):

Term 1

MEDC0075: Bioinformatics and Structural Biology as applied to Drug Design
MEDC0076: Target Identification, Pharmacology and High Throughput Screening
MEDC0077: Cheminformatics and Modelling for Drug Design
MEDC0078: Biological Molecules as Therapeutics - Antibodies, siRNA, and Stem Cells

Term 2

MEDC0079: Biophysical screening methods, X-ray crystallography, protein NMR and phenotypic screening.
MEDC0080: Fragment-based Drug Design
MEDC0081: Target Selection - Scientific Grounds
MEDC0082: Target Selection - Commercial and Intellectual Property Aspects
MEDC0066: Practical Laboratory Research Skills

Research Project and Dissertation

MEDC0084 - 105 credits - start January.

All students undertake an independent research project which culminates in a dissertation of 15,000 to 20,000 words. Research project - minimum 5 months and can be selected from expert groups in UCL - e.g. Cancer Institute, Royal Free Hospital, MRC Laboratory for Molecular Biology, Medicine, etc. Examples of research projects are as follows:

Screening, Biology, Cell Biology and Biochemistry
Optimization of small molecule drug inhibition of a kinase targets for therapy of Polycystic Kidney Disease
Towards novel antibiotics: small molecule inhibitors of the serine/threonine protein kinases of Gram positive bacterial pathogens
Probing host-HIV interactions using small molecule inhibitors
Medicinal Chemistry
Exploration of a new scaffold as a potential new class of a kinase inhibitor
Modified analogues of an established scaffold with potential for the treatment of neurodegenerative conditions
Computational, Cheminformatics, Bioinformatics, and computer-based literature projects
Drug repositioning using internal technology
Fragment-based design of peptidomimetic drugs
Natural hormones and neurotransmitters as drug leads
Structural and Molecular Biology
Crystal structure determination of protein-ligand complexes
Cloning and NMR study of Drug protein target
PK/ADME, Assay development
Development of PK/ADME assay for a Cancer project

Teaching and Learning 

The programme is delivered through a combination of lectures, seminars, tutorials and problem classes, critical journal clubs and research project. Assessment is through coursework, practicals, laboratory work, examination, dissertation and oral presentation.


There are no optional modules for this programme.