Wolfson Institute for Biomedical Research
Publications in the WIBR 2020

- Tsutsumi S, Chadney O, Yiu T-Y, Bäumler E, Faraggiana L, Beau M, Hausser M (2020) Purkinje Cell Activity Determines the Timing of Sensory-Evoked Motor Initiation Cell Reports https://doi.org/10.1016/j.celrep.2020.108537
- Fişek, M., & Häusser, M. (2020). Are Human Dendrites Different?. Trends in Cognitive Sciences. doi:10.1016/j.tics.2020.03.002
- Dalgleish, H. W. P., Russell, L. E., Packer, A. M., Roth, A., Gauld, O. M., Greenstreet, F., . . . Häusser, M. (2020). How many neurons are sufficient for perception of cortical activity?. Elife, 9. doi:10.7554/eLife.58889
- Adams, A., Bjaalie, J. G., Deshler, J. O., De Koninck, Y., Egan, G., Illes, J., . . . Yuste, R. (2020). International Brain Initiative: An Innovative Framework for Coordinated Global Brain Research Efforts. NEURON, 105 (2), 212-216. doi:10.1016/j.neuron.2020.01.002
- Arlt, C., & Häusser, M. (2020). Microcircuit Rules Governing Impact of Single Interneurons on Purkinje Cell Output In Vivo. Cell Rep, 30 (9), 3020-3035.e3. doi:10.1016/j.celrep.2020.02.009
- The International Brain Laboratory, Aguillon-Rodriguez, V., Angelaki, D., Bayer, H., Bonacchi, N., Carandini, M., . . . Zador, A. (2020). Standardized and reproducible measurement of decision-making in mice. doi:10.1101/2020.01.17.909838
- Robinson, N. T. M., Descamps, L. A. L., Russell, L. E., Buchholz, M. O., Bicknell, B. A., Antonov, G. K., . . . Häusser, M. (2020). Targeted Activation of Hippocampal Place Cells Drives Memory-Guided Spatial Behavior. Cell. doi:10.1016/j.cell.2020.09.061
- Theofanous, S. A., Florens, M. V., Appeltans, I., Denadai Souza, A., Wood, J. N., Wouters, M. M., & Boeckxstaens, G. E. (2020). Ephrin-B2 signaling in the spinal cord as a player in post-inflammatory and stress-induced visceral hypersensitivity. Neurogastroenterol Motil, e13782. doi:10.1111/nmo.13782
- MacDonald, D. I., Wood, J. N., & Emery, E. C. (2020). Molecular mechanisms of cold pain. Neurobiology of Pain, 7, 100044. doi:10.1016/j.ynpai.2020.100044
- Heegde, F. T., Luiz, A. P., Santana-Varela, S., Magnusdottir, R., Hopkinson, M., Chang, Y., . . . Chenu, C. (2020). Osteoarthritis-related nociceptive behaviour following mechanical joint loading correlates with cartilage damage. Osteoarthritis Cartilage. doi:10.1016/j.joca.2019.12.004
- de Clauser, L., Santana-Varela, S., Wood, J. N., & Sikandar, S. (2020). Physiologic osteoclasts are not sufficient to induce skeletal pain in mice. Eur J Pain. doi:10.1002/ejp.1662
- de Clauser, L., Luiz, A. P., Santana-Varela, S., Wood, J. N., & Sikandar, S. (2020). Sensitization of cutaneous primary afferents in bone cancer revealed by in vivo calcium imaging. Cancers, 12 (12), 1-19. doi:10.3390/cancers12123491
- Alles, S. R. A., Nascimento, F., Luján, R., Luiz, A. P., Millet, Q., Bangash, M. A., . . . Wood, J. N. (2020). Sensory neuron–derived NaV1.7 contributes to dorsal horn neuron excitability. Science Advances, 6 (8), eaax4568. doi:10.1126/sciadv.aax4568
- Cox, J., Woods, C. G., & Kurth, I. (2020). Peripheral sensory neuropathies – pain loss vs. pain gain. Medizinische Genetik. doi:10.1515/medgen-2020-2039
- Conole, D., Chou, Y. -. T., Patsiarika, A., Nwabo, V., Dimitriou, E., Soudy, C., . . . Selwood, D. (2020). Discovery of a novel fluorescent chemical probe suitable for evaluation of neuropilin-1 binding of small molecules. Drug Development Research. doi:10.1002/ddr.21641
- Colpitts, C. C., Ridewood, S., Schneiderman, B., Warne, J., Tabata, K., Ng, C. F., . . . Towers, G. J. (2020). Hepatitis C virus exploits cyclophilin A to evade PKR. Elife, 9. doi:10.7554/eLife.52237
- Bertrand, J. A., Schicht, M., Stamer, W. D., Baker, D., Sherwood, J. M., Lütjen-Drecoll, E., . . . Overby, D. R. (2020). The β4-Subunit of the Large-Conductance Potassium Ion Channel KCa1.1 Regulates Outflow Facility in Mice. Investigative ophthalmology & visual science, 61 (3), 41. doi:10.1167/iovs.61.3.41
- Kim, J., Lana, B., Torelli, S., Ryan, D., Catapano, F., Ala, P., . . . Lin, Y. -. Y. (2019). A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan. EMBO Rep, e47967. doi:10.15252/embr.201947967
- Lu, Y., Wang, Y., Zhang, Z., Huang, J., Yao, M., Huang, G., . . . Wang, W. (2020). Generation of Chicken IgY against SARS-COV-2 Spike Protein and Epitope Mapping. Journal of Immunology Research, 2020, 1-8. doi:10.1155/2020/9465398
- Li, K., Wei, S., Hu, L., Yin, X., Mai, Y., Jiang, C., . . . Zhao, B. (2020). Protection of Fecal Microbiota Transplantation in a Mouse Model of Multiple Sclerosis. Mediators of Inflammation, 2020, 1-13. doi:10.1155/2020/2058272
- Dreosti, E., & López-Schier, H. (2020). Animal Behaviour: Learning Social Distancing. Current Biology, 30 (20), R1275-R1276. doi:10.1016/j.cub.2020.08.072
- Dreosti, E., Hoffman, E. J., & Rihel, J. (2020). Behavioral and Neural Genetics of Zebrafish. In R. T. Gerlai (Ed.), Modeling autism spectrum disorders in zebrafish. Academic Press.
- Dreosti, E. (2020). Nurturing nature. Elife, 9. doi:10.7554/eLife.61323
- Tunbak, H., Vazquez-Prada, M. C., Ryan, T. M., Kampff, A. R., & Dreosti, E. (2020). Whole-brain mapping of socially isolated zebrafish reveals that lonely fish are not loners. Elife, 9. doi:10.7554/eLife.55863
- Michoud, F., Seehus, C., Schönle, P., Brun, N., Taub, D., Zhang, Z., . . . Lacour, S. P. (2020). Epineural optogenetic activation of nociceptors initiates and amplifies inflammation. Nat Biotechnol. doi:10.1038/s41587-020-0673-2
- Talbot, S., Doyle, B., Huang, J., Wang, J. -. C., Ahmadi, M., Roberson, D. P., . . . Woolf, C. J. (2020). Vagal sensory neurons drive mucous cell metaplasia. Journal of Allergy and Clinical Immunology. doi:10.1016/j.jaci.2020.01.003
- Tsuchiya, Y., Byrne, D. P., Burgess, S. G., Bormann, J., Baković, J., Huang, Y., . . . Gout, I. (2020). Covalent Aurora A regulation by the metabolic integrator coenzyme A. Redox Biology, 28. doi:10.1016/j.redox.2019.101318
- Bellany, F., Tsuchiya, Y., Tran, T. M., Chan, A. W. E., Allan, H., Gout, I., & Tabor, A. B. (2020). Design and synthesis of Coenzyme A analogues as Aurora kinase A inhibitors: An exploration of the roles of the pyrophosphate and pantetheine moieties.
Bioorganic & Medicinal Chemistry, 28 (22), 115740. doi:10.1016/j.bmc.2020.115740 - Guo, J., Douangamath, A., Song, W., Coker, A. R., Edith Chan, A. W., Wood, S. P., . . . von Delft., F. (2020). In crystallo-screening for discovery of human norovirus 3C-like protease inhibitors. Journal of Structural Biology: X, 100031. doi:10.1016/j.yjsbx.2020.100031
- Greenwood, S. O. R., Chan, A. W. E., Hansen, D. F., & Marson, C. M. (2020). Potent non-hydroxamate inhibitors of histone deacetylase-8: Role and scope of an isoindolin-2-yl linker with an α-amino amide as the zinc-binding unit. Bioorganic and Medicinal Chemistry Letters. doi:10.1016/j.bmcl.2019.126926
- Scott, O. B., & Chan, A. W. E. (2020). ScaffoldGraph: an open-source library for the generation and analysis of molecular scaffold networks and scaffold trees. Bioinformatics. doi:10.1093/bioinformatics/btaa219
- Edith Chan, A. W. (2020). The shape of artificial intelligence: Just a black box?. CHEMICAL BIOLOGY & DRUG DESIGN, 96 (3), 882-885. doi:10.1111/cbdd.13793