TINs Seminar: Key Physiological Techniques for the Regenerative Medicine field and beyond

Please note: This event is a hybrid event. As the venue has limited capacity, in-person tickets will be reserved exclusively for UCL staff. Online tickets are available to everyone. If you wish to attend in person, please ensure you register using your UCL email address. Registrations without a valid UCL email will be cancelled.

This is an event organised by Dr Conor McCann and the Regenerative Medicines Therapeutic Innovation Networks* (TINs), and supported by UCL Translational Research Office and NIHR Great Ormond Street Hospital Biomedical Research Centre - The Tissue Engineering and Regenerative Medicine theme.

Who shall attend this event:

Basic and translational researchers from across UCL are encouraged to attend in person and external delegates are welcome to join remotely.

Why should you attend this event:

The event aims to showcase functional assays and physiological techniques which may be useful across the wider RegMed field to increase understanding of applications and expertise that are needed and are available within UCL to monitor the effectiveness of therapies. Techniques to be discussed include: Calcium Imaging, Patch clamp, Extracellular electrophysiology / Multielectrode arrays, Intracellular microelectrode electrophysiology, Organ bath contractility, and other imaging modalities which are relevant to many research fields. Interesting insights in this area will also be provided by GenScript and Cairn Research. The event will close with an interactive roundtable discussion and delegates will have the opportunity to explore what techniques could be used to address their specific research questions.

The Regenerative Medicines TIN aims to remove barriers and reach out to researchers at all career stages across departments and research areas. We highlight case studies of Regenerative Medicine at UCL, providing insights into the work of the Therapeutic Innovation Networks and an example of projects looking for collaborators to accelerate translation.

Venue:

Leolin Price Lecture Theatre, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH

Agenda

13:30 – 13:35 Welcome and presentation of the TIN (Prof. Jonathan Knowles- Regenerative TIN Chair, UCL Eastman Dental Institute)

13:35 – 13:55 Intracellular electrophysiology (Professor and CSO Tom Otis - Sainsbury Wellcome Centre/UCL)

13:55 – 14:15 Patch clamp electrophysiology (Dr Nathanael O’Neill - UCL Queen Square Institute of Neurology)

14:15 – 14:35 Extracellular electrophysiology/multi-electrode arrays (Dr Mihaly Kollo - Francis Crick Institute)

14:35 – 14:50 GenScript accelerating your research (Dr.rer.nat. Christopher Ford - GenScript)

14:50 – 15:10 Coffee break

15:10 – 15:30 Calcium imaging to assess functional regeneration of the heart (Prof. Sean Davidson - The Hatter Cardiovascular Institute, Institute of Cardiovascular Science, UCL)

15:30 – 15:50 Organ bath contractility and its utility in gut regenerative medicine (Dr Conor McCann - Stem Cells and Regenerative Medicine , UCL Great Ormond Street Institute of Child Health)

15:50 – 16:10 Optogenetic stimulation of the neuromuscular system (Dr Barney Bryson - UCL Queen Square Institute of Neurology, Department of Neuromuscular Diseases)

16:10 – 16:25 The openFrame: as much microscope as you need (Greg Perry - Cairn Research)

16:25 – 16:55 Roundtable Q&A

16:55 – 17:00 Closing remarks (Dr Conor McCann and Prof. Jonathan Knowles)

17:00 – 18:00 Networking drinks

Microsoft Teams meeting link will be provided to online participants prior to the event.

Etiquette and sustainability

Places are limited and on a first-come-first-served basis. To reduce waste and prevent people from missing out, please make sure to cancel your order if you are no longer able to attend.