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UCL Queen Square Institute of Neurology

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The Centre is based at the Institute of Neurology, Queen Square and directed by Professor Francesco Muntoni, a Paediatric Neurologist who holds a dual appointment in both institutions (IoN QS and GOSH ICH). The Centre spearheads activities in this rapidly evolving area and plays a major role in translational neuroscience at UCL.

 

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This new Centre was established at QSION initially, and subsequently at the new £281m Translational Neuroscience building on Grays Inn Road in 2024. It will combine laboratory and clinical expertise focused on neurological, neuromuscular and neurodegenerative disorders, their mechanisms of disease and cutting-edge RNA and AAV gene therapy expertise and foster cross-institutional collaborations between QSION and GOSICH.

In the last five years a number of extremely effective RNA and adeno-associated viral vectors therapies have dramatically improved the outcomes for individuals affected by a range of neurological disorders, mostly affecting children. The focus of this new Centre will be to harness the learning derived from these recent successes, from mechanistic insight discovery, to early and late translational research and eventually regulatory approval, and apply it to a wider group of neurodegenerative disorders. The activities of the Centre will be highly complementary with established activities and expertise in both institutes, including in the Zayed Centre, the Dementia Research Institute, the Sigrid Rausing Neurogenetics Therapies Programme and the two NIHR Biomedical Research Centres translational research programmes (UCLH and GOSH).

 

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Translational Research Office

UCL Translational Research Office (TRO) is an integral part of UCL’s biomedical research powerhouse. As an expert team of applied scientists and business developers, we support our researchers in realising their translational ambition by offering strategic advice, funding support, and bridging the gap with industry to help establish collaborations that drive the pipeline of therapeutic, device and diagnostic innovations.

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Mentoring at IoN

Mentoring enables people to achieve their potential through a work-based relationship between two parties who are not connected within a line management structure. 

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QS IoN seminars take place across many of our research groups, departments and teams. Our researchers and educators use diverse, creative and exciting activities and techniques to communicate their ideas to all audiences.