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UCL Queen Square Institute of Neurology

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ReCAPS

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The ReCAPS Study is investigating changes in cortical excitability after stroke, in patients with upper limb impairment. Research suggests that cortical excitability can differ in the early and chronic post-stroke phases, and that these differences may correspond with changes in the rate of recovery.

 The study is also exploring the therapeutic potential of non-invasive brain stimulation to enhance brain plasticity. We are assessing whether the effects of brain stimulation differ when applied early compared to late after stroke, and whether current flow modelling can be used to dose-control stimulation and reduce variability in outcome measures.

 For more information about the study, please go to the ReCAPS Study website

Biomarkers of early stroke recovery (BEST) study

Previous research has found that it is very difficult to predict whether stroke survivors with a severely impaired arm will recover well or not. This study involves measuring brain activity, using magnetoencephalography (MEG), magnetic resonance imaging (MRI) and transcranial magnetic stimulation (TMS), to identify neurological biomarkers that may help us to understand the process of recovery. In the future we may be able to use these biomarkers to predict how well stroke survivors will recover. This is important as it will help to provide individually tailored rehabilitation therapy.