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UCL Queen Square Institute of Neurology

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Dr Umesh Vivekananda

Honorary Senior Research Fellow

Clinical & Experimental Epilepsy

UCL Queen Square Institute of Neurology

Joined UCL
1st Feb 2023

Research summary

My PhD was entitled 'Presynaptic action potential modulation in a neurological channelopathy' and involved using a novel high resolution microscopy technique termed Hopping Probe Ion Conductance Microscopy or HPICM to demonstrate

1. The first reported channel recordings from submicrometer sized presynaptic boutons in hippocampal neuronal culture

2. The effect of Kv1.1 on action potential waveform and analog-digital facilitation in the channelopathy Episodic Ataxia Type 1.

My postdoctoral research is now focussing on human epilepsy and in particular the use of

1. MEG and the development of novel room temperature OPM sensors for functional imaging of epileptic activity

2. Intracranial EEG (involving stimulation) and single unit recording to further understand epileptogenesis and cognition in epilepsy

3. Use of ex vivo human tissue for genetic analysis and the role of calcium dynamics in the epileptic brain

Teaching summary

Primary supervisor for three MSc Neuroscience students, Research Associate 

Secondary supervisor for PhD candidate, BSc student

Education

Oriel College Oxford
Other higher degree, Master of Arts/Bachelor of Arts |
University College London
Doctorate, Doctor of Philosophy | 2017
King's College London
Doctorate, Bachelor of Medicine/Bachelor of Surgery | 2007
King's College London
First Degree, Bachelor of Science | 2004

Biography

MRC New Investigator 2020-

NIHR Future Leader 2020

Clinical Research Associate, DCEE, Institute of Neurology 2017-2018

Neurology registrar St George's Hospital 2015-2017

Wellcome Trust Clinical Research Training Fellow 2011-2015

Publications