Prof James Jepson
Professor of Neurogenetics
Clinical & Experimental Epilepsy
UCL Queen Square Institute of Neurology
- Joined UCL
- 1st Jun 2014
The primary goal of my lab is to use the fruit fly, Drosophila, as a model to understand the molecular and cellular mechanisms of neurological disease, particularly those involving involuntary movements (such as dystonia and dyskinesia) and seizures. To do so, we utilise an array of state-of-the-art techniques, including gene editing, electrophysiology, optical imaging, transcriptomics, and genetic modifier screens. In parallel, we have an interest in characterising novel genes and neural circuits influencing sleep in Drosophila.
Dr. Jepson lectures on several MSc courses at UCL, including Human Genetics and Clinical Neuroscience. His lectures focus on the use of Drosophila as a model to understand the mechanistic basis of neurological disease, and patho-mechanisms underling hyperkinetic movement disorders such as dystonia and dyskinesia.