Acute optic neuritis: a review and proposed protocol

Optic neuritis is an inflammatory optic neuropathy that is frequently- but not always - associated with multiple sclerosis (MS). Despite recent developments in laboratory, imaging and electrophysiological techniques, no consensus guidelines have yet been formulated for the diagnostic work-up in patients presenting with optic neuritis.

In this Review, published in Nature Reviews Neurology, Dr Petzold (Department of Neuroinflammation, UCL Institute of Neurology) and colleagues contribute to the development of such a consensus by proposing an investigation protocol for optic neuritis.

The aims are to aid recognition of patients at risk of severe visual loss, to contribute to future attempts at classification of optic neuritis, and to provide end points for clinical studies.

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Further information: 

Petzold, A. et al. The investigation of acute optic neuritis: a review and proposed protocol. Nature Reviews Neurology. Available online 8th July 2014. doi:10.1038/nrneurol.2014.108