UCL Institute of Health Informatics



VIVALDI Study 2020-2023

The original VIVALDI Study was a national project launched to investigate COVID-19 infections in care homes. The aim of the study was to find out how many care home staff and residents were infected with COVID-19, how effective vaccines are against infection, and to inform decisions around the best approach to COVID-19 testing.


The study ran from June 2020 and 31 March 2023.

VIVALDI Social Care Study

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Expanding on what we learned from the original VIVALDI Study, the VIVALDI Social Care Study aims to reduce the impact of infections and outbreaks in care homes. The study will use routinely collected data by the NHS and public health agencies to measure levels of common infections in care home residents and will generate an anonymised database that can be used for research.


The pilot study will run from November 2023.

VIVALDI Clinical Trial

The VIVALDI Clinical Trial was set up to find out if regularly testing staff who don’t have symptoms for COVID-19 reduce residents’ chance of getting severely ill, by stopping staff from spreading infection.


The study will run from November 2022 to April 2024.

VIVALDI Serum Biobank

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A subset of blood samples collected between 2020 and 2023 from participants of the original VIVALDI Study, have been stored in the VIVALDI Serum Biobank. Upon request, these can be made available to other researchers investigating biological responses to infection in older people.

VIVALDI Publications

Our full list of publications is available online.