Neonatal brain injury resulting from oxygen deprivation around the time of birth affects 1 to 3 per 1000 live term births worldwide. Hypoxic-ischemic encephalopathy accounts for one million deaths each year. The affected infants die in the neonatal period or sustain neurological deficits, including cerebral palsy, epilepsy and cognitive disabilities. The severity and lifelong nature of these incapacities have a large socio-economic impact on the individual, family and healthcare system.
Development of new therapeutic strategies to ameliorate the severity or even prevent brain injury resulting from hypoxic-ischaemic encephalopathy