Perinatal Mortality Prevention & Care

UCL Stillbirth & Serious incident Prevention and Research Centre (SPaRC)

The SPaRC centre will integrate stillbirth care, investigation and prevention research conducted at UCL, Great Ormond Street Hospital, and other partners and collaborators.

Projects include the development and testing of a placenta histopathology database, studies to improve our understanding and detection of gestational diabetes, and studies of fetal growth restriction led by the UCL Fetal Medicine research team.

There is close collaboration with the Stillbirth Centre for Research Excellence in Queensland, Australia.

Learning from Deaths – Perinatal Mortality Reviews

Siassakos is lead for parental involvement aspects of the new PMRTool, and for a wide portfolio of studies which investigated, developed, and tested a process to make parental involvement feasible and useful (the PARENTS portfolio).

npeu.ox.ac.uk/pmrt/programme

ncbi.nlm.nih.gov/pmc/articles/PMC5781014/

obgyn.onlinelibrary.wiley.com/doi/abs/10.1002/uog.20139

bmjopen.bmj.com/content/8/11/bmjopen-2018-023792

Core Outcome Set for Care after Stillbirth (iCHOOSE)

An NIHR Research Training Fellow (supervised by Siassakos) is co-developing with bereaved parents and other experts a Core Outcome Set (COS) to be used in all future trials of interventions after stillbirth. comet-initiative.org/studies/details/775

Global Bereavement Care

We lead a global collaboration established after the Lancet stillbirth series 2016 to investigate and agree a set of core and aspirational global bereavement care principles, with support by the WHO and the International Stillbirth Alliance, and the Stillbirth Advocacy Working Group.

Lancet: sciencedirect.com/science/article/pii/S0140673615008363?via%3Dihub

Global Principles of Care: obgyn.onlinelibrary.wiley.com/doi/full/10.1111/1471-0528.15430

Microbiome of Recurrent Miscarriage

We are collaborating in a Bristol-led NIHR-funded study to understand and develop treatments for recurrent miscarriage.