Wolfson Institute for Biomedical Research


Scanning electron micrograph of the dendrites of a cerebellar Purkinje cell - Hausser Lab


Wolfson Institute for Biomedical Research

The Wolfson Institute for Biomedical Research was established at UCL in 1995 for the pursuit of excellence in translational biomedical research. Now, with its primary focus on fundamental and translational neuroscience, the WIBR is a key hub within the rich environment of the UCL neuroscience community.
Lab Research Photo


The WIBR is currently home to 14 Principal Investigators, including established senior academics as well as early-career scientists. Collectively we hold more than £25m in grants from The European Research Council, MRC, BBSRC, Wellcome and other biomedical research charities.

Teaching in lab


Researchers within the WIBR organise and contribute to several distinguised undergraduate modules within the School of Life and Medical Sciences. The Institute has around 20 current PhD students, and runs a highly rated one-year MSc degree course in Drug Design.

wood lab group photo


Contact details for WIBR staff

Contact Us (WIBR)

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Our address and location

Andrei O

MRes Drug Design Programme

The MRes Drug Design programme, with research projects hosted by labs from the Wolfson Institute for Biomedical Research offers advanced training in cutting edge neuroscience-related techniques.


WIBR History

Find out more about WIBR history

2023 Publications

Pryce, Gareth; Sisay, Sofia; Giovannoni, Gavin; Selwood, David L; Baker, David; (2023) Neuroprotection in an Experimental Model of Multiple Sclerosis via Opening of Big Conductance, Calcium-Activated Potassium Channels.Pharmaceuticals , 16 (7) , Article 972. 10.3390/ph16070972

Buller, Sophie; Kohnke, Sara; Hansford, Robert; Shimizu, Takahiro; Richardson, William D; Blouet, Clemence; (2023) Median eminence myelin continuously turns over in adult mice.Molecular Metabolism , Article 101690. 10.1016/j.molmet.2023.101690. (In press). 

Kessaris, Nicoletta; Denaxa, Myrto; (2023) Cortical interneuron specification and diversification in the era of big data.Current Opinion in Neurobiology , 80 , Article 102703. 10.1016/j.conb.2023.102703

Fuller, Alice M; Luiz, Ana; Tian, Naxi; Arcangeletti, Manuel; Iseppon, Federico; Sexton, Jane E; Millet, Queensta; ... Sikandar, Shafaq; + view all (2023) Gate control of sensory neurotransmission in peripheral ganglia by proprioceptive sensory neurons.Brain , Article awad182. 10.1093/brain/awad182. (In press). 

Fişek, Mehmet; Herrmann, Dustin; Egea-Weiss, Alexander; Cloves, Matilda; Bauer, Lisa; Lee, Tai-Ying; Russell, Lloyd E; (2023) Cortico-cortical feedback engages active dendrites in visual cortex.Nature , 617 (7962) pp. 769-776. 10.1038/s41586-023-06007-6

Mikaeili, H., Habib, A. M., Yeung, C. W. -. L., Santana-Varela, S., Luiz, A. P., Panteleeva, K., . . . Cox, J. J. (2023). Molecular basis of FAAH-OUT-associated human pain insensitivityBrain, awad098. doi:10.1093/brain/awad098

Gao, L., Zhao, J. -. X., Qin, X. -. M., & Zhao, J. (2023). The ethanol extract of Scutellaria baicalensis Georgi attenuates complete Freund's adjuvant (CFA)-induced inflammatory pain by suppression of P2X3 receptorJournal of Ethnopharmacology, 116762. doi:10.1016/j.jep.2023.116762

Jami, S., Deuis, J. R., Klasfauseweh, T., Cheng, X., Kurdyukov, S., Chung, F., . . . Vetter, I. (2023). Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 functionNature Communications, 14, 2442. doi:10.1038/s41467-023-37963-2

Iseppon, F., Luiz, A. P., Linley, J. E., & Wood, J. N. (2023). Pregabalin silences oxaliplatin-activated sensory neurons to relieve cold allodyniaeNeuro, ENEURO.0395-ENEU22.2022. doi:10.1523/ENEURO.0395-22.2022

Qin, Q., Wang, M., Li, H., Xu, Z. D., & Tang, Y. (2023). Editorial: The role of microglia in the pathogenesis of neurodegenerative diseasesFrontiers in Aging Neuroscience, 14, 1105896. doi:10.3389/fnagi.2022.1105896

Zhu, W., Li, W., Jiang, J., Wang, D., Mao, X., Zhang, J., . . . Li, N. (2023). Chronic salmon calcitonin exerts an antidepressant effect via modulating the p38 MAPK signaling pathwayFrontiers in Molecular Neuroscience, 16, 1071327. doi:10.3389/fnmol.2023.1071327

Wang, Tao; Zhou, Yunxia; Fan, Yunping; Duan, Hao; Guo, Xiaoyu; Chang, Jinlong; Jiang, Youheng; ... Li, Ningning; + view all (2023) PERK-Mediated Cholesterol Excretion from IDH Mutant Glioma Determines Anti-Tumoral Polarization of Microglia.Advanced Science , Article e2205949. 10.1002/advs.202205949. (In press).