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The PRIMROSE Programme of Research

The PRIMROSE project was a five year programme of research funded by the National Institute for Health Research's Programme Grants for Applied Research (RP-PG-0609-10156)

PRIMROSE was a NIHR funded programme of research to improve the assessment and management of cardio vascular risk in people with severe mental illnesses such as bipolar disorder, psychosis and schizophrenia.

We delivered a suite of studies to improve CVD risk management between 2011 and 2019.

Our questions included:

  • How do we best assess CVD risk in people with SMI?
  • What are the best intervention components to manage CVD risk in people with SMI?
  • Can a nurse led/HCA intervention be successfully delivered across UK primary care?
  • Is such an intervention effective and cost effective?
  • Do medications such as statins help to prevent CVD risk in people with SMI?

The final NIHR report of the whole Primrose programme is available below:

Osborn et al 2019. https://www.journalslibrary.nihr.ac.uk/pgfar/pgfar07020#/abstract

The scientific summary, with all main findings can be found at: https://www.journalslibrary.nihr.ac.uk/pgfar/pgfar07020#/scientific-summary