UCL Institute of Ophthalmology


Development, Ageing and Disease Theme

Fundamental mechanisms and discovery

Leads: Professor Adnan Tufail and Professor Pete Coffey


There is an urgent need for new therapeutics for eye disease. We investigate the underlying biological mechanisms so we can identify new therapeutic targets and develop novel therapies. Our labs are using molecular and cellular modelling, molecular dissection techniques such as proteomics, lipidomics and metabolomics in combination with genetic studies that allows us to better understand the pathways involved so that we can develop better treatments.

Our principal investigators in this theme are: