Prof Astrid Limb

Research summary

My research is focused on the investigation of various aspects of retinal stem cell biology and the pathogenesis of retinal inflammatory disease.  At present my group is investigating cellular and molecular mechanisms that prevent regeneration of the adult human retina, as well as the application of Müller glial stem cells to cell replacement therapies to treat major retinal degenerations. Work in my laboratory includes retinal transplantation in experimental models of retinal degeneration, development of enriched neural cell populations with functional activity in vitro, use of biomaterials for retinal cell transplantation, visual function assessment by electrophysiology, examination of signalling pathways of neural progenitors in Müller stem cells and identification of inhibitory molecules that prevent endogenous neural regeneration in the human retina.

Education

Royal College of Pathologists, UK

FRCPath, Ophthalmology | 2009

Brunel University

PhD, Immunology | 1986

Universidad Javeriana

MSc, Microbiology | 1979

Publications