UCL Queen Square Institute of Neurology


Amyotrophic Lateral Sclerosis (Lou Gehrig's disease)

Medline NLM Definition: A disease marked by progressive degeneration of the neurons giving rise to the corticospinal tract and of the motor cells of the brain stem and spinal cord, and resulting in a deficit of upper and lower motor neurons.

see also Motor Neurone Disease and support groups page

Amyotrophic Lateral Sclerosis: factsheet from NINDS, the National Institute of Neurological Disorders and Stroke (US site)

Amyotrophic Lateral Sclerosis: information from NORD, the National Organization for Rare Disorders (US site)

Amyotrophic Lateral Sclerosis: information from the NHS website

Amyotrophic Lateral Sclerosis: information from Patient UK website

PubMed Medline search on Amyotrophic Lateral Sclerosis (ALS)

Support Groups

See Motor Neurone Disease page for UK support groups which offer help to those with ALS & MND.

ALS Association
US website giving up-to-date information on ALS.

PatientsLikeMe - ALS/Motor Neuron Disease Forum
US site with UK members. Patients share their treatments and outcomes not just to help themselves, but to help others.

ALS Society of Canada
The ALS Society funds medical research into the cause of and cure for Lou Gehrig's Disease. National support activities also include the development and production of public awareness and educational materials and a quarterly journal for people with ALS, their families and their healthcare providers.

Brain and Spine Foundation
Information on living with a neurological condition and on diagnosis. There are publications and resources. The useful glossary of neurological conditions (under 'Information and support') includes links to some other organisations as well as to Brain and Spine Foundation information.

Neurological Alliance
Collective voice for 80 organisations, including stroke and brain injury. Organisations are listed at https://www.neural.org.uk/our-members/, a good place to start if looking for information on those conditions. Site also includes information about living with a neurological condition, a glossary, and information about onset and diagnosis as well as a small set of real life stories.

NHS Inform: brain, nerves and spinal cord 
NHS inform is Scotland's national health information service, with the aim of providing the people in Scotland with accurate and relevant information to help them make informed decisions about their own health and the health of the people they care for.