Wellcome / EPSRC Centre for Interventional and Surgical Sciences


Brain surgery with Robotics, Artificial Intelligence, and Neuronavigation (BRAIN)

The BRAIN group is an interdisciplinary collaboration between surgeons at the National Hospital for Neurology and Neurosurgery and engineers at the Wellcome ESPRC Centre for Interventional and Surgical Sciences (WEISS). Our aim is to develop and apply novel technology to make neurosurgery safer and more effective for patients, simpler for surgeons, and more efficient for healthcare systems, including those in resource-limited settings.

Surgical device

Research Focus

Our principal areas of research focus include:

  • Surgical robotics
  • Artificial intelligence
  • Neuronavigation
  • Clinical translation of technology

Clinical Focus

Our principal areas of clinical focus include:

  • Pituitary surgery and skull base surgery
  • Neuro-oncological surgery
  • Neurovascular surgery

Collaborating Academic Centres

We collaborate with international and national institutes and centres of excellence, including:

  • Wellcome ESPRC Centre for Interventional and Surgical Sciences (WEISS), UCL, London, UK
  • Hamlyn Centre for Robotic Surgery, Imperial College London, UK
  • School of Biomedical Engineering and Imaging Sciences, King's College London, UK
  • Endomin Centre for Endoscopic and Minimally Invasive Neurosurgery, Hirslanden, Zurich, Germany
  • Department of Clinical Neurosciences, University of Calgary, Canada
  • CRUK Brain Tumour Centre, University of Edinburgh, Scotland

Collaborating Companies

We work with engineers of novel technologies, including: 

  • Medtronic
  • Artificial Bits
  • Olympus
  • VineHealth
  • Storz
  • BBraun
  • Lightpoint Medical


Clinical Lead - Hani Marcus

Engineering Lead - Danail Stoyanov

Find out more about the BRAIN group on their website