HIV Surveillance
All HIV-exposed infants and any children and young people diagnosed with HIV (seen by paediatric services), should be reported to ISOSS using the secure online portal. Enhanced data collection is carried out for all vertical transmissions in England-born children. All cases are reviewed by the Infectious Diseases in Pregnancy Screening Programme's HIV Clinical Expert Review Panel, in order to establish the circumstances surrounding the transmissions to inform national guidelines and policy.
Long-Term Follow-Up
Following notification of any diagnosed children and young people to ISOSS, all patients seen for paediatric HIV care in England are followed-up until transition to adult care by the Children's HIV and AIDS Reporting System (CHARS)
Syphilis Reporting
All infants born to women who are treated for syphilis/require treatment in pregnancy are reported to ISOSS, as well as any cases of congenital syphilis. Enhanced data collection is carried out for all cases of congenital syphilis in England-born children. All cases are reviewed by the Infectious Diseases in Pregnancy Screening Programme's Congenital Syphilis Clinical Expert Review Panel in order to establish the circumstances surrounding the transmissions to inform national guidelines and policy.
Congenital Rubella
Congenital rubella is a notifiable disease, however as we work closely with the UKHSA if you have seen a child with congenital rubella born in England, please also contact the ISOSS Team directly using nhs.net (england.isoss@nhs.net).

Please refer to our online Paediatric User Guide for a step-by-step guide and handy tips to ISOSS online reporting.
Contact Us: ISOSS Team, Population, Policy & Practice, UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London WC1N 1EH Email: england.isoss@nhs.net Follow @isoss_ucl