Division of Infection and Immunity


Dr Mohlopheni Jackson Marakalala

Associate Professor, UCL
Faculty Member, AHRI
Wellcome Trust International Intermediate Fellow


Research in the Marakalala lab focuses on understanding basic biology of TB immunopathogenesis to guide development of new diagnostic and therapeutic tools.

Research summary

Dr Mohlopeni Marakalala’s group’s core interest is in developing TB biomarkers and host-directed therapies by studying factors associated with disease progression using lung tissue and blood samples from TB patients. The group are also interested in various cell death modalities in the mononuclear phagocyte system and their role in TB immunopathogenesis. The group’s other focus is on understanding strategies utilized by Mycobacterium tuberculosis to subvert the host immune system.

Selected publications