Division of Infection and Immunity


UCL researchers identify tissue-resident CD8 T cells in human liver

4 July 2017

The study was recently published in The Journal of Experimental Medicine.

UCL Portico

The Maini Group recently published a paper in The Journal of Experimental Medicine (JEM), where they identified tissue-resident memory CD8 T cells that are compartmentalised in the healthy human liver, that expand in controlled hepatotropic infection and can swiftly produce antiviral cytokines.

These T cells form the prototype to inform the development of liver-targeted T cell immunotherapy.

The paper is accompanied by a well written Insights article in the same issue, plus a cover image showing an artistic representation of a liver infected with HBV by artist Emilie Clark.

New York artist Emilie Clark's work has featured in numerous publications including The New York Times, The New Yorker, and The Wall Street Journal.