Division of Infection and Immunity


IIT Seminar | Professor Andrew MacDonald

18 February 2021, 12:00 pm–1:00 pm

'Dendritic cells and macrophages in promotion and regulation of type-2 inflammation'

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Dr Anne Pesenacker

Professor Andrew MacDonald (Division of Infection, Immunity & Respiratory Medicine, University of Manchester) will be speaking at the UCL Institute of Immunity and Transplantation Seminar Series on Thursday 18 February.

All are welcome to attend. Please contact Fran Jackson (f.jackson@ucl.ac.uk) if you would like to join the seminar, or meet the speaker.

About the speaker

The research in my laboratory mainly investigates how pathogen interaction with the innate immune system influences the development of adaptive immunity and inflammation.  My particular interest is Type 2 inflammation, which is responsible for widespread suffering in allergy, as well as being a hallmark of infection with parasitic worms (helminths). 

Our work addresses some outstanding fundamental questions about the role of a specialised type of immune cell – the dendritic cell (DC) – in orchestration of Type 2 inflammation.  DCs are centrally involved in initiation of immune responses in most settings, but the precise mechanisms by which they direct Type 2 inflammation are currently not known.

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