IIT Seminar | Dr Chris Tape
15 November 2018, 12:00 pm–1:00 pm
'Single-Cell Signalling Analysis of Heterocellular Organoids'
Event Information
Open to
- All
Organiser
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Dr Victoria Male (Host)
Location
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Tutorial Room 14UCL Medical School, Royal Free CampusRowland Hill StreetLondonNW3 2QGUnited Kingdom
Dr Chris Tape of the Research Department of Oncology at the UCL Cancer Institute will be speaking at the UCL Institute of Immunity and Transplantation Seminar Series on Thursday 15 November. The seminar will be held in Tutorial Room 14 at the UCL Medical School Royal Free Campus.
Like healthy intestinal tissue, colorectal tumours contain epithelial, stromal, lymphoid, and myeloid cells. And like healthy tissues, colorectal tumours use these different cells to achieve complex phenotypes. The difference in cancer is that these phenotypes (such as immune evasion and metastasis) can kill, rather than aid, the host organism. Unfortunately, we know very little about how the different cell types in cancer communicate with one another to drive tumours. Dr Tape’s lab studies how oncogenic mutations (e.g. loss of APC, oncogenic KRAS) communicate with stromal and immune cells to drive colorectal cancer. By understanding how mutations regulate all cell types within a tumour, they hope to discover novel approaches to treat cancer.
All are welcome to attend. If you would like to meet the speaker after the seminar please contact the host.