Division of Infection and Immunity


IIT Seminar | Dr Chris Tape

15 November 2018, 12:00 pm–1:00 pm

'Single-Cell Signalling Analysis of Heterocellular Organoids'

Event Information

Open to



Dr Victoria Male (Host)


Tutorial Room 14
UCL Medical School, Royal Free Campus
Rowland Hill Street
United Kingdom

Dr Chris Tape of the Research Department of Oncology at the UCL Cancer Institute will be speaking at the UCL Institute of Immunity and Transplantation Seminar Series on Thursday 15 November. The seminar will be held in Tutorial Room 14 at the UCL Medical School Royal Free Campus.

Like healthy intestinal tissue, colorectal tumours contain epithelial, stromal, lymphoid, and myeloid cells. And like healthy tissues, colorectal tumours use these different cells to achieve complex phenotypes. The difference in cancer is that these phenotypes (such as immune evasion and metastasis) can kill, rather than aid, the host organism. Unfortunately, we know very little about how the different cell types in cancer communicate with one another to drive tumours. Dr Tape’s lab studies how oncogenic mutations (e.g. loss of APC, oncogenic KRAS) communicate with stromal and immune cells to drive colorectal cancer. By understanding how mutations regulate all cell types within a tumour, they hope to discover novel approaches to treat cancer.

All are welcome to attend. If you would like to meet the speaker after the seminar please contact the host.

Further information