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The below is a depiction of stable isotope labelling kinetics (SILK) methodology and was published in Paterson et al. 2019. The full article can be accessed here.
Paterson RW, Gabelle A, Lucey BP, Barthelemy NR, Leckey CA, Hirtz C, Lehmann S, Sato C, Patterson BW, West T, Yarasheski K, Rohrer JD, Wildburger NC, Schott JM, Karch CM, Wray S, Miller TM, Elbert DL, Zetterberg H, Fox NC, Bateman RJ. SILK studies - capturing the turnover of proteins linked to neurodegenerative diseases. Nat Rev Neurol. 2019 July; 15(7):419-427. doi:10.1038/s41582-019-0222-0.