Dementia Research Centre


Professor Sebastien Ourselin

  • Head of the Translational Imaging Group
  • Director of the EPSRC Centre for Doctoral Training in Medical Imaging
  • Professor of Medical Image Computing

Prof Sebastien Ourselin…

Prof Ourselin is the Head of the Translational Imaging Group (TIG) within the UCL Centre for Medical Image Computing (CMIC), Director of the EPSRC Centre for Doctoral Training in Medical Imaging, CMIC Deputy Director, Head of Image Analysis at the Dementia Research Centre (DRC), and Professor of Medical Image Computing. He leads the translational imaging research program between CMIC and the UCL Institute of Neurology, and in collaboration with Prof Nick Fox of the DRC established a new imaging unit at Queen Square to deliver novel imaging biomarkers for clinical trials. He is also an associate editor of IEEE Transactions on Medical Imaging and a member of the Editorial Board of Medical Image Analysis. He has been a MICCAI Board Member since 2008, and was elected Executive Secretary of the MICCAI Society (2009-2012). His main research interests include image registration, segmentation, molecular imaging, atlas conception, statistical shape modelling, surgical simulation, image-guided therapy and minimally invasive surgery. He has been involved in a broad range of clinical projects, including neuroimaging, neurosurgery, computer-assisted cardiovascular surgery, radiotherapy treatment, colonoscopy, and orthopaedic imaging. His research is often collaborative, involving clinical and commercial partners.

In collaboration with the DRC and IXICO, his team focus on the development of novel imaging biomarkers. This is done taking advantage of state-of-the-art algorithms developed within CMIC and the internationally leading clinical research at UCL to design robust and innovative software for clinical trials (Phase 2 and 3). As part of the team's effort to translate image analysis tools to the clinic, they are also strongly involved in fast image processing using GPU and support of the open source community. Specifically, the team has developed a set of self-contained software packages for image registration (NiftyReg), segmentation (NiftySeg), reconstruction (NiftyRec), and for biomechanical modelling (NiftySim).