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Dr Ione Woollacott

  • MRC Clinical Research Fellow

Dr Ione Woollacott…

Dr Ione Woollacott is a Specialist Registrar in Neurology with an interest in cognitive neurology, particularly young onset and inherited dementias.  She is funded by an MRC Clinical Research Training Fellowship, supervised by Dr Jonathan Rohrer, Professor Henrik Zetterberg and Dr Tammaryn Lashley.

Ione’s clinical and research interests are in the aetiology, diagnosis and treatment of progressive neurodegenerative cognitive disorders, particularly sporadic and familial forms of frontotemporal dementia (FTD).  Her PhD aims to explore the role of neuroinflammation in FTD and her research involves studying both symptomatic patients with familial and sporadic FTD and, in familial cases, their pre-symptomatic at-risk relatives. She aims to establish histopathological and cerebrospinal fluid biomarkers of different FTD subtypes, focusing on markers of inflammation, and to assess how levels of identified biomarkers correlate with imaging and neuropsychological measures of FTD.

She also participates in Dr Rohrer’s Cognitive Disorders clinic at the National Hospital for Neurology and Neurosurgery and performs clinical assessments and lumbar punctures for the Genetic Frontotemporal Dementia Initiative (GENFI) at UCL.