Welcome to the Towers Lab




We believe Brexit is bad for science

Towers Lab before and after Brexit

And migration is good.





We aim to understand the molecular details of host virus interactions, to develop novel therapeutic approaches for viral infection and to use viruses to help us understand mammalian cell biology and evolution. For a lay summery of our work, visit the BRC review of Jane's work published in Nature: 'Discovery of HIV 'invisibility cloak' reveals new treatment opportunities'


                                         


News

Read more about the Towers lab news on our News page.



Recent Publications, 2016

Nature

Our collaborative work "HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis" with Dr Leo James has been accepted in Nature.

Journal of Virology

We have also recently published with Dr Julia García Pradoin Journal of Virology. Jimenez E, Ruiz A, Kløverpris HN, Rodriguez-Plata MT, Peña R, Blondeau C, Selwood DL, Izquierdo-Useros N, Moris A, Clotet B, Goulder P, Towers GJ, Prado JG. Non-human TRIM5 variants enhance recognition of HIV-1-infected cells by CD8+ T cells. (J Virol. 2016 Jul 20. pii: JVI.00819-16. [Epub ahead of print] PMID: 27440884),

Journal of Biological Chemistry

We have published with Prof David Selwood in Journal Of Biological Chemistry.

Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AW, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL. Selective Inhibition of the Mitochondrial Permeability Transition Pore Protects against Neurodegeneration in Experimental Multiple Sclerosis (J Biol Chem. 2016 Feb 26;291(9):4356-73. doi: 10.1074/jbc.M115.700385. Epub 2015 Dec 17. PMID: 26679998).



BSc results, July 2016

Mei and Elysia


Congratulations to our summer students Meiyin Lin (UCL) and Elysia Upton (Imperial College London) who achieved firsts in their BSc degrees.



Postdoctoral Vacancies, July 2016

We will soon be advertising for 2 Research Associates for posts funded by a Wellcome Trust Senior Fellowship entitled “Characterisation of innate immune DNA sensing and viral evasion strategies”. Check back for more information in late August/early September or go to our recruitment page.



Cold Spring Harbor Retrovirus Meeting, May 2016

Rich Miles defends his poster

The Towers Lab attended the Retrovirus meeting at Cold Spring Harbor.



The Towers lab presented posters at Keystone, March 2016 

MariaT presents her poster at Keystone conference 2016

MariaT, Becky, Lucy and Greg attended the 2016 Keystone conference on HIV Persistence: Pathogenesis and Eradication (X7) at Squaw Creek - Olympic Valley, California, USA. MT and Greg presented posters.



Richard Miles has secured a fellowship to go to New York, Jan 2016

Richard has secured the Charlotte and Yule Bogue Research Fellowship to visit the lab of Professor Singer in New York.



Dr Doug Fink wins funding for his PhD, Jan 2016

Dr Doug Fink

Doug has secured a Wellcome Trust Clinical Research Training Fellowship at UCL.



Towers Lab Christmas do, Dec 2015

Towers lab Christmas do at 'Watch Me'. Alun Vaughan-Jackson, Chris Monit, Chris Tie, Kat Sutherland, Lucy Thorne, Dami Collier, Teresa Rodriguez-Plata, isobel Honeyborne, Claire Kerridge, Carolina Ferreira, Jane Rasaiyaah, Calire Pardieu, Stephane Hue, Jane Turner, Greg Towers, Ecco Staller, Doug King, Doug Fink, Jade Donovan, Hataf Khan, Choon Ping Tan, David Stirling, Jo Rowley, Dejan Mesner, Clare Jolly, Laura Hilditch, Richard Miles, Petra Mlcochova

The Towers lab and friends took their annual curry pilgrimage to 'Watch Me' in South Wimbledon for Christmas



Senior Research Fellowship renewal, July 2015

Dr Joe Grove, Prof Greg Towers, Dr Ravi Gupta and Dr Clare Jolly celebrate securing Wellcome Trust grants

Congratulations to Prof Greg Towers who, along with Dr Clare Jolly, Dr Ravi Gupta and Dr Joe Grove, secured grants from the Wellcome Trust to fund their labs for the next 5 years!

The Division of Infection and Immunity hosted celebrations in the UCL Quad to congratulate it's 4 successful PI's.



Cold Spring Harbor, May 2015

Torstein Schaller and Greg at CSH 2015

Laura presented at the 2015 Retrovirus meeting in Cold Spring Harbor



Embo Paper, May 2015

The lab celebrates Adam's Ubiquitin paper getting into EMBO

Adam's article "TRIM5a requires Ube2W to anchor Lys63-linked ubiquitin chains and restrict reverse transcription" has been published in EMBO.



Sierra Leone, April 2015

Sample Reception at Port Loko PHE laboratory, Sierra Leone

The Towers lab has sent volunteers to West Africa to help with the international response to the Ebola outbreak. Jane Turner spent 5 weeks working in a diagnostic lab run by GOAL at their Ebola Treatment Centre in Port Loko.



Keystone, April 2015

Tan presented at the 2015 Innate Immunity and Determinants of microbial Pathogenesis conference run by Keystone Symposia in Silverthorne, Colorado.



Mucosal surfaces, reproductive health and HIV in prevention research Workshop, Jan 2015

Jane R and Teresa presented at the 2015 Mucosal surfaces, reproductive health and HIV in prevention research Workshop in Cape Town, South Africa.









We are funded by Senior Biomedical Research Fellowship from the Wellcome Trust No 090940 to Professor Greg Towers and also by: a European Research Council Advanced Award, a Medical Research Council confidence in concept award, a UCL Business proof of concept award, the National Institute for Health Research (NIHR) University College London Hospitals Biomedical Research Centre and the UCL MRC Centre for Medical Molecular Virology.


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Page last modified on 05 jul 16 22:24 by Jane Lorna Elizabeth Turner