Welcome to the Towers Lab
We believe Brexit is bad for science
And migration is good.
We aim to understand the molecular details of host virus interactions, to develop novel therapeutic approaches for viral infection and to use viruses to help us understand mammalian cell biology and evolution. For a lay summery of our work, visit the BRC review of Jane's work published in Nature: 'Discovery of HIV 'invisibility cloak' reveals new treatment opportunities'
Chris has been filming in South Africa for a new BBC documentary on the history of HIV.
John Walter has won a Wellcome Turst Large Arts Award to be resident artist in the Towers Lab, June 2016
John has secured a Wellcome Trust Large Arts Award (number:203868/Z/16/Z) for his project "CAPSID"
Greg, Richard and Dr Chris visited Gayhurst to teach about the incredible world of viruses, bacteria and other pathogens.
Greg and Chris presented 'Viruses: Sneezes and Gore' at the Cheltenham Science Fair on 6th June
The Operation Ouch team filmed Dr Chris Van Tulleken (Dr Chris) studying for his PhD in the Towers Lab.
Greg was interviewed by Dr Chris Van Tulleken in his documentary investigating the risk of an Ebola outbreak in the UK. How easy is it to catch? Could the virus improve it's methods of transmission? Watch 'Could I get Ebola?' on BBC iPlayer.
Doctors Chris and Xand Van Tulleken were featured in the Evening Standard's Life & Style Magazine. To read about Chris' circuitous route into HIV research, click here.
Carlton School visited our teaching labs. The children precipitated DNA, spooling it out in long strings shown below, and learned how to pipette before designing their own viruses complete with the horrible diseases they would cause.
Click for some pictures of the visit.
Dr Chris Van Tulleken celebrated winning the MRC’s Max
Perutz Science Writing award at the Royal Institution in London this month.
Visit our news page to read his article “Ex
Africa Semper Aliquid Novo”.
Read more about the Towers lab news on our News page.
Our collaborative work "HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis" with Dr Leo James has been accepted in Nature.
Journal of Virology
We have also recently published with Dr Julia García Pradoin Journal of Virology. Jimenez E, Ruiz A, Kløverpris HN, Rodriguez-Plata MT, Peña R, Blondeau C, Selwood DL, Izquierdo-Useros N, Moris A, Clotet B, Goulder P, Towers GJ, Prado JG. Non-human TRIM5 variants enhance recognition of HIV-1-infected cells by CD8+ T cells. (J Virol. 2016 Jul 20. pii: JVI.00819-16. [Epub ahead of print] PMID: 27440884),
Journal of Biological Chemistry
We have published with Prof David Selwood in Journal Of Biological Chemistry.
J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L,
Walker P, Simone MI, Chan AW, Towers GJ, Coker AR, Duchen MR, Szabadkai
G, Baker D, Selwood DL. Selective Inhibition of the Mitochondrial Permeability Transition Pore
Protects against Neurodegeneration in Experimental Multiple Sclerosis (J Biol Chem. 2016 Feb 26;291(9):4356-73. doi: 10.1074/jbc.M115.700385. Epub 2015 Dec 17. PMID: 26679998).
Congratulations to our summer students Meiyin Lin (UCL) and Elysia Upton (Imperial College London) who achieved firsts in their BSc degrees.
We will soon be advertising for 2 Research Associates for posts funded by a Wellcome Trust Senior Fellowship entitled “Characterisation of innate immune DNA sensing and viral evasion strategies”. Check back for more information in late August/early September or go to our recruitment page.
The Towers Lab attended the Retrovirus meeting at Cold Spring Harbor.
MariaT, Becky, Lucy and Greg attended the 2016 Keystone conference on HIV Persistence: Pathogenesis and Eradication (X7) at Squaw Creek - Olympic Valley, California, USA. MT and Greg presented posters.
Richard has secured the Charlotte and Yule Bogue Research Fellowship to visit the lab of Professor Singer in New York.
Doug has secured a Wellcome Trust Clinical Research Training Fellowship at UCL.
The Towers lab and friends took their annual curry pilgrimage to 'Watch Me' in South Wimbledon for Christmas
Congratulations to Prof Greg Towers who, along with Dr Clare Jolly, Dr Ravi Gupta and Dr Joe Grove, secured grants from the Wellcome Trust to fund their labs for the next 5 years!
The Division of Infection and Immunity hosted celebrations in the UCL Quad to congratulate it's 4 successful PI's.
Laura presented at the 2015 Retrovirus meeting in Cold Spring Harbor
Adam's article "TRIM5a requires Ube2W to anchor Lys63-linked ubiquitin
chains and restrict reverse transcription" has been published in EMBO.
The Towers lab has sent volunteers to West
Africa to help with the international response to the Ebola outbreak. Jane
Turner spent 5 weeks working in a diagnostic lab run by GOAL at their Ebola
Treatment Centre in Port Loko.
Tan presented at the 2015 Innate Immunity and Determinants of microbial Pathogenesis conference run by Keystone Symposia in Silverthorne, Colorado.
Jane R and Teresa presented at the 2015 Mucosal surfaces, reproductive health and HIV in prevention research Workshop in Cape Town, South Africa.
We are funded by Senior Biomedical Research Fellowship from the Wellcome Trust No 090940 to Professor Greg Towers and also by: a European Research Council Advanced Award, a Medical Research Council confidence in concept award, a UCL Business proof of concept award, the National Institute for Health Research (NIHR) University College London Hospitals Biomedical Research Centre and the UCL MRC Centre for Medical Molecular Virology.
Page last modified on 05 jul 16 22:24 by Jane Lorna Elizabeth Turner