Welcome to the Towers Lab
We aim to understand the molecular details of host virus interactions, to develop novel therapeutic approaches for viral infection and to use viruses to help us understand mammalian cell biology and evolution.
An exploding virus and a model HIV capsid are displayed by John Walter, our artist in residence in Infection, at the Edinbrugh Sculpture Workshop.
Chris has been filming in South Africa for a new BBC documentary on the history of HIV.
John Walter has won a Wellcome Turst Large Arts Award to be resident artist in the Towers Lab, June 2016
John has secured a Wellcome Trust Large Arts Award (number:203868/Z/16/Z) for his project "CAPSID"
Greg, Richard and Dr Chris visited Gayhurst to teach about the incredible world of viruses, bacteria and other pathogens.
Greg and Chris presented 'Viruses: Sneezes and Gore' at the Cheltenham Science Fair on 6th June.
Read more about the Towers lab news on our News page.
EMBO J publication, Jan 2017
Dr Petra Mlcochova from our colaborators, the Gupta group, has had her paper 'A G1‐like state allows HIV‐1 to bypass SAMHD1 restriction in macrophages' published in EMBO J.
Dr Doug Fink and Dr Oseme Etomi at the Nigerian Institute of Medical Research in Lagos, Nigeria as part of a visit supported by the UCL Development Fund.
Our collaborative work with Dr Leo James has been published in Nature.
David A. Jacques, William A. McEwan, Laura Hilditch, Amanda J. Price, Greg J. Towers, Leo C. James. HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesis. Nature. 2016 Aug 18;536(7616):349-53
Journal of Virology
We have also recently published with Dr Julia García Pradoin Journal of Virology.
Jimenez E, Ruiz A, Kløverpris HN, Rodriguez-Plata MT, Peña R, Blondeau C, Selwood DL, Izquierdo-Useros N, Moris A, Clotet B, Goulder P, Towers GJ, Prado JG. Non-human TRIM5 variants enhance recognition of HIV-1-infected cells by CD8+ T cells. (J Virol. 2016 Jul 20. pii: JVI.00819-16. [Epub ahead of print] PMID: 27440884),
Journal of Biological Chemistry
We have published with Prof David Selwood in Journal Of Biological Chemistry.
J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L,
Walker P, Simone MI, Chan AW, Towers GJ, Coker AR, Duchen MR, Szabadkai
G, Baker D, Selwood DL. Selective Inhibition of the Mitochondrial Permeability Transition Pore
Protects against Neurodegeneration in Experimental Multiple Sclerosis (J Biol Chem. 2016 Feb 26;291(9):4356-73. doi: 10.1074/jbc.M115.700385. Epub 2015 Dec 17. PMID: 26679998).
Congratulations to our summer students Meiyin Lin (UCL) and Elysia Upton (Imperial College London) who achieved firsts in their BSc degrees.
We will soon be advertising for 2 Research Associates for posts funded by a Wellcome Trust Senior Fellowship entitled “Characterisation of innate immune DNA sensing and viral evasion strategies”. Check back for more information in late August/early September or go to our recruitment page.
The Towers Lab attended the Retrovirus meeting at Cold Spring Harbor.
MariaT, Becky, Lucy and Greg attended the 2016 Keystone conference on HIV Persistence: Pathogenesis and Eradication (X7) at Squaw Creek - Olympic Valley, California, USA. MT and Greg presented posters.
Richard has secured the Charlotte and Yule Bogue Research Fellowship to visit the lab of Professor Singer in New York.
Doug has secured a Wellcome Trust Clinical Research Training Fellowship at UCL.
The Towers lab and friends took their annual curry pilgrimage to 'Watch Me' in South Wimbledon for Christmas.
We are funded by Senior Biomedical Research Fellowship from the Wellcome Trust No 090940 to Professor Greg Towers and also by: a European Research Council Advanced Award, a Medical Research Council confidence in concept award, a UCL Business proof of concept award, the National Institute for Health Research (NIHR) University College London Hospitals Biomedical Research Centre and the UCL MRC Centre for Medical Molecular Virology.
Page last modified on 08 feb 17 10:43 by Jane Lorna Elizabeth Turner