Personalised Medicine

Personalised Medicine News

Small vessels inside a cystic kidney with disorganised vasculature

New treatment for polycystic kidney disease

A new technique for treating polycystic kidney disease has been identified by researchers based at the UCL Institute of Child Health. Published in the Journal of the American Society of Nephrology, the treatment, which involves targeting tiny blood and lymphatic vessels inside the kidneys, is shown to improve renal function and slow progression of disease in mice. More...

Published: Jun 3, 2015 1:26:36 PM

Chemotherapy machine

Chemo before surgery benefits patients with advanced ovarian cancer

Women with advanced ovarian cancer have fewer side effects and tend to have a better quality of life if given chemotherapy before surgery, according to a Cancer Research UK funded study published in The Lancet. More...

Published: May 20, 2015 1:32:26 PM

Ashtray

Smoking induces early signs of cancer in cheek swabs

DNA damage caused by smoking can be detected in cheek swabs, finds research published today in JAMA Oncology. The study provides evidence that smoking induces a general cancer program that is also present in cancers which aren’t usually associated with it – including breast and gynaecological cancers. More...

Published: May 14, 2015 4:05:32 PM

Mycobacterium tuberculosis

New test could identify resistant tuberculosis faster in London

Tuberculosis (TB) disease rates in some parts of London are as high as in Sub-Saharan Africa, and drug-resistant strains are becoming increasingly common. These require specific treatments, and if doctors know that a bug is resistant they can start therapy earlier, often leading to better outcomes. More...

Published: May 13, 2015 4:44:22 PM

Ovarian cancer under the microscope

New screening technique could pick up twice as many ovarian cancer cases

A new screening method can detect twice as many women with ovarian cancer as conventional strategies, according to the latest results from the largest trial of its kind led by UCL. More...

Published: May 5, 2015 5:14:50 PM

Scanning electromicrograph of an HIV-infected H9 T cell

Human immune system can control re-awakened HIV, suggesting ‘kick and kill’ cure is possible

The human immune system can handle large bursts of HIV activity and so it should be possible to cure HIV with a ‘kick and kill’ strategy, finds new research led by UCL, University College London Hospitals (UCLH) NHS Foundation Trust, the University of Oxford and the University of North Carolina at Chapel Hill. More...

Published: Apr 13, 2015 11:15:06 AM

Professor Sibylle Mittnacht interviewed by Clare Hastings at The Institute of Cancer Research, London

New role uncovered for ‘oldest’ tumour suppressor gene

Scientists have revealed a brand new function for one of the first cancer genes ever discovered – the retinoblastoma gene – in a finding that could open up exciting new approaches to treatment. More...

Published: Mar 27, 2015 12:25:07 PM

Man on scales

Weight discrimination has major impact on quality of life

Weight discrimination is linked to significantly lower quality of life, and accounts for approximately 40% of the negative psychological effects associated with obesity, finds new UCL research funded by Cancer Research UK. More...

Published: Mar 24, 2015 10:37:30 AM

The regions of ancient British, Irish and Saxon control in the 7th Century

The first fine-scale genetic map of the British Isles

Many people in the UK feel a strong sense of regional identity, and it now appears that there may be a scientific basis to this feeling, according to a landmark new study into the genetic makeup of the British Isles. More...

Published: Mar 19, 2015 11:14:17 AM

Colorectal cancer tumour

Cancer fear can impact screening uptake

People who worry about cancer are more likely to want to get screened for colon cancer, but feeling uncomfortable at the thought of cancer makes them less likely to actually go for the test, finds new UCL-led research. More...

Published: Jan 29, 2015 10:49:05 AM

Clinic

£14M to develop HIV self-testing in southern Africa

A partnership involving UCL has been awarded £14M to accelerate access to simple self-tests in African countries. Self-testing for HIV using rapid diagnostic kits is becoming increasingly widely used, allowing high-risk people to test their own HIV status in private. More...

Published: Dec 4, 2014 12:46:00 PM

Eve Appeal

Family history screening misses people at high risk of cancer

UCL research into the BRCA gene mutation in the Jewish population show that only assessing family history misses half of the people with the mutation. More...

Published: Dec 1, 2014 12:46:00 PM

Image showing how tetanus neurotoxin (red) binds to areas rich in nidogen-2 (green)

Secret of tetanus toxicity offers new way to treat motor neuron disease

The way that tetanus neurotoxin enters nerve cells has been discovered by UCL scientists, who showed that this process can be blocked, offering a potential therapeutic intervention for tetanus. This newly-discovered pathway could be exploited to deliver therapies to the nervous system, opening up a whole new way to treat neurological disorders such as motor neuron disease and peripheral neuropathies. More...

Published: Nov 28, 2014 9:10:00 AM

Blood for transplant

UCL awarded £4.2 million for stem cell transplantation and immunotherapy

UCL has been awarded £4.2 million from the National Institute for Health Research (NIHR) to fund a Blood and Transplant Research Unit for stem cell transplantation and immunotherapy, due to launch in October 2015. More...

Published: Nov 4, 2014 3:56:00 PM

UCL Quad

UCL awarded £13.5 million to advance medical research facilities

As part of the Clinical Research Infrastructure Initiative, UCL has been awarded £13.5 million for a number of projects to help advance clinical research. More...

Published: Oct 23, 2014 2:50:00 PM

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