Cardiovascular Project Newsletter
The UCL Cardiovascular Gene Annotation newsletter is now available. Nancy and Jess have been annotating protein-protein interactions related to telomere maintenance and protection, Ruth and Rachael attended the GO Consortium meeting and our website has been given a facelift - take a look.
New BHF funded PSICQUIC dataset
We are pleased to announce that Tony Sawford, at the EBI, has created a new PSICQUIC dataset which can be used in Cytoscape analysis. The EBI-GOA-nonIntAct dataset includes all of the protein interaction data that has been created by the Gene Ontology (GO) Consortium.Tweets by @UCLgene
Neurological Gene Annotation
The Neurological Gene Annotation project is focused on Gene
Ontology (GO) annotation of Parkinson's Disease-relevant proteins. To find out more about Parkinson's Disease, please see the Parkinson's UK website.
Annotations contributed by this project to the GO Consortium dataset are attributed to ParkinsonsUK-UCL.
By using GO to curate scientific literature we are creating a resource for the Parkinson’s Disease community that will enable researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research.
See our latest news and progress in our current newsletter.
What we curate
We contribute Gene Ontology annotations for proteins to the GO Consortium.
A high-priority set of Parkinson's Disease-relevant genes have been selected based on genetic linkage or association studies:
A larger set of proteins were chosen based on their interaction with high-priority proteins or because of their role in Parkinson's-related biological processes and includes the gene products from the list above:
Example of curated protein: human LRRK2.
You can contribute by
Page last modified on 22 sep 15 15:58
The work of the Cardiovascular Gene Annotation group is supported by British Heart Foundation grant RG/13/5/30112. The work of the Neurological Gene Annotation group is supported by Parkinson's UK grant G-1307. The Functional Gene Annotation team is supported by the National Institute for Health Research University College London Hospitals Biomedical Research Centre.