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Neurological Gene Annotation

The Parkinson’s UK Gene Ontology Project represents a collaboration between University College London and the European Bioinformatics Institute (EBI), funded by Parkinson's UK.  This annotation team is a part of the GO Consortium.

The Gene Ontology (GO) vocabulary is the established standard for the functional annotation of gene products. By using GO to curate scientific literature and by integrating results from high-quality high-throughput experiments we will create an information-rich resource for the Parkinson’s disease community, enabling researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research.  We are selecting and prioritizing genes related to Parkinson’s disease, based on multiple lines of evidence, for annotation. 

Every GO annotation made is attributed to an identified source, such as a unique publication identifier (PubMed ID or PMID), and an indication of the type of evidence that supports the association between the gene product and the GO term.  For an example, see the record of the LRRK2 protein – this is a focus of ongoing annotation efforts. Annotations contributed by this project to the GO consortium dataset are listed as ParkinsonsUK-UCL.

We welcome feedback from scientists, in particular those studying Parkinson’s and parkinson-like disease.  We encourage researchers to review the annotation of their 'favourite' gene and suggest information that may be missing, inaccurate or incomplete in these annotations. 

Comments and suggestions can be sent via

email: goannotation@ucl.ac.uk


The work of the Parkinson’s Gene Annotation group is supported by Parkinson's UK grant G-1307

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Page last modified on 06 nov 14 21:16



The work of the Cardiovascular Gene Annotation group is supported by British Heart Foundation grant RG/13/5/30112. The work of the Neurological Gene Annotation group is supported by Parkinson's UK grant G-1307.