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Neurological Gene Annotation

The Neurological Gene Annotation project is focused on Gene Ontology (GO) annotation of neurological-relevant proteins. We contribute GO annotations for proteins to the GO Consortium, the attribution they are given is determined by the focus of the funded project. An example of a curated protein is human LRRK2.

Annotations contributed by this project to the GO Consortium dataset are attributed to ParkinsonsUK-UCL, ARUK-UCL or SynGO-UCL.

By using GO to curate the scientific literature we are creating a resource for the Parkinson’s, Alzheimer's and neurological research communities that will enable researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research.

See our latest news and progress in our current newsletter.

What we curate

Parkinson's

Alzheimer's

SynGO

We have prioritised 329 Parkinson's-associated proteins for curation, and have provided comprehensive annotation for 48 priority genes. 

Parkinson's UK funded this project and provides more information about Parkinson's disease.

This 6 month project will focus on using GO terms to capture the role of 60 Alzheimer’s disease-relevant amyloid-beta binding proteins, as described in PMID:26719327.

Alzheimer's research UK (ARUK) funds this project and provides more information about Alzheimer's disease.

We are contributing to the SynGO project. This is an international collaborative effort to provide location and functional information about synaptic proteins.

Contribute

You can contribute by

  • reviewing the annotation of your favourite gene and telling us what's missing or inaccurate (or tell us if we've done a good job!)
  • suggesting papers for curation
  • Contact Us