Neurological Gene Annotation
By using Gene Ontology (GO) to curate scientific literature and by integrating results from high-throughput experiments we will create an information-rich resource for the Parkinson’s disease community, enabling researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research. Every GO annotation made is attributed to an identified source, such as a unique publication identifier (PubMed ID or PMID), and an indication of the type of evidence that supports the association between the gene product and the GO term. For an example, see the record of the LRRK2 protein – this is one focus of our ongoing annotation efforts. Annotations contributed by this project to the GO consortium dataset are attributed to ParkinsonsUK-UCL.
We are selecting and prioritizing genes related to Parkinson’s disease, based on multiple lines of evidence, for annotation. To date, we have prioritised over 200 Parkinson’s-relevant proteins for annotation:
We welcome feedback from scientists, in particular those studying Parkinson’s and Parkinson's-like diseases. We encourage researchers to review the annotation of their 'favourite' gene and suggest information that may be missing, inaccurate or incomplete in these annotations.
Comments and suggestions can be sent via
• email: firstname.lastname@example.org
The work of the Parkinson’s Gene Annotation group is supported by Parkinson's UK grant G-1307
Page last modified on 05 dec 14 09:57
The work of the Cardiovascular Gene Annotation group is supported by British Heart Foundation grant RG/13/5/30112. The work of the Neurological Gene Annotation group is supported by Parkinson's UK grant G-1307.