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Neurological Gene Annotation

The Neurological Gene Annotation project is focused on Gene Ontology (GO) annotation of neurological-relevant proteins

Annotations contributed by this project to the GO Consortium dataset are attributed to ParkinsonsUK-UCL or SynGO-UCL. To find out more about Parkinson's Disease, please see the Parkinson's UK website. The SynGO website provides more information about the Synapse Biology Annotation Initiative.

By using GO to curate the scientific literature we are creating a resource for the Parkinson’s Disease and neurological research communities that will enable researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research.

See our latest news and progress in our current newsletter.

What we curate

Proteins

We contribute Gene Ontology annotations for proteins to the GO Consortium.

A high-priority set of Parkinson's Disease-relevant genes have been selected based on genetic linkage or association studies:

A larger set of proteins were chosen based on their interaction with high-priority proteins or because of their role in Parkinson's-related biological processes and includes the gene products from the list above: 

Example of a curated protein: human LRRK2.

Contribute

You can contribute by

  • reviewing the annotation of your favourite gene and tell us what's missing or inaccurate (or tell us if we've done a good job!)
  • suggesting papers for curation
  • Contact Us