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Neurological Gene Annotation



Overview

The Neurological Gene Annotation project is focused on Gene Ontology (GO) annotation of Parkinson's Disease-relevant proteins. To find out more about Parkinson's Disease, please see the Parkinson's UK website.

Annotations contributed by this project to the GO Consortium dataset are attributed to ParkinsonsUK-UCL.

By using GO to curate scientific literature we are creating a resource for the Parkinson’s Disease community that will enable researchers to rapidly evaluate and interpret existing data and generate hypotheses to guide future research.

See our latest news and progress in our current newsletter.


What we curate

Proteins

We contribute Gene Ontology annotations for proteins to the GO Consortium.

A high-priority set of Parkinson's Disease-relevant genes have been selected based on genetic linkage or association studies:

A larger set of proteins were chosen based on their interaction with high-priority proteins or because of their role in Parkinson's-related biological processes and includes the gene products from the list above: 

Example of curated protein: human LRRK2.


Contribute

You can contribute by

  • reviewing the annotation of your favourite gene and tell us what's missing or inaccurate (or tell us if we've done a good job!)
  • suggesting papers for curation
  • Contact Us