The Functional Gene Annotation team captures the following functional information for cardiovascular-relevant gene products.

Gene Ontology (GO)

We use the GOA curation tool to associate terms from the GO to gene products including proteins, RNAs and macromolecular complexes. The data we produce is incorporated into the GOA and GO Consortium databases.

Protein-protein interactions

We use the IntAct editing tool to capture interactions at a very detailed level as described in the IMEx guidelines. These annotations are directly incorporated into the IntAct database, from where they are exported to the IMEx Consortium database.

All of our annotations are propagated to popular freely available online knowledgebases, such as UniProt, Ensembl and NCBIGene as well as numerous other public and commercial analysis tools.