Cardiovascular Gene Ontology
The Cardiovascular Gene Ontology Annotation Initiative represents a collaboration between University College London and the European Bioinformatics Institute (EBI), funded by the British Heart Foundation. This annotation group is a member of the GO Consortium.
This collaboration builds on our previous effort to fully describe heart development with GO terms. The new ontology, presented in Khodiyar VK et al., 2011, describes heart morphogenesis, the differentiation of specific cardiac cell types and the involvement of signalling pathways in heart development. As a result of this project the number of GO terms describing heart development has been expanded from 12 to over 285.
We aim to annotate 4,000 cardiovascular-associated genes to the existing ontology:
We are currently extending our field of annotation to specific cardiac-related processes, such as lipid metabolism and cardiac conduction.
For an example, see the annotation record of the fully annotated APOA4 protein.
We welcome feedback from cardiovascular scientists. We encourage researchers to review the annotation of their 'favourite' gene and suggest information that may be missing, inaccurate or incomplete in these annotations.
Comments and suggestions can be sent via
- email: firstname.lastname@example.org
Page last modified on 10 mar 14 17:46
The work of the Cardiovascular Gene Annotation group is supported by British Heart Foundation grant RG/13/5/30112. The work of the Neurological Gene Annotation group is supported by Parkinson's UK grant G-1307.