Wolfson Institute for Biomedical Research


Scanning electron micrograph of the dendrites of a cerebellar Purkinje cell - Hausser Lab


MEDC0076 Module 2:The biology of drug discovery programmes

Module Structure: (15 credits each) • Lectures and Tutorials • Assessment: 50% coursework, 50% unseen examination.

Module Title

Module 2:     The biology of drug discovery programmes
Module CodeMEDC0076
Module LeaderDr Edith Chan
Short description

What are the most important drug targets? The biology and pharmacology of the 5 major protein families will be explored. Drugs and drug action for each of the family will be explored in depth, including major experimental techniques. Emphasis on how to interpret the biological data from common experiments is stressed. Statistics for Biology will be taught and different modern techniques for target identification will be explored.

Module aims

  • To understand the pharmacology of the main protein targets in drug discovery
  • To learn statistics for Biology
  • To learn how to interpret the biological data, such as Kd,  IC50.
  • To understand the modern technology of identification of drug targets, such as microarray.


List of Lectures and Tutorials

  • Pharmacology of the main drug targets
  • Biological data for drug discovery
  • Statistics for drug discovery
  • Identification of drug targets
  • Learn to use Origin
  • Learn statistical functions for biology
  • Journal Club
Module assessment 50% course work + 50% unseen 1 hour exam