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Rapid Fermentation Process Design (MBI Training, Bioprocess Industries)

  • 24 hours (approx)
  • 4 days
  • 17 Oct 2022

Overview

This four-day online course will teach you how to design and specify bioreactors.

You'll learn how to apply microscale techniques in rapid fermentation process development and scale-up.

The course is aimed at fermentation scientists and engineers and those in established fermentation development groups.

This course is part of the Modular Training for the Bioprocess Industries programme (MBI), run by the Department of Biochemical Engineering at UCL.

Course content and structure

Teaching will be online. You'll be taught in small classes, with an emphasis on interactive problem solving and case studies.

Each day will cover the following topics:

Day 1

  • Power consumption in gassed and ungassed bioreactors
  • Scale-up: effects of scale and scale-up strategies
  • Oxygen mass transfer in bioreactors
  • Case study: design of a bioreactor

    Day 2

    • Tutorial: scale-up from shake flasks to stirred bioreactors
    • Bioreactor mixing
    • Bioreactor scale-down: strategies and devices
    • The ambr™ advanced micro bioreactor system automate high-throughput screening and process development studies for both cell and microbial culture processes

    Day 3

    • Tutorial: high-throughput process development
    • Case study: predictive scale-up based on microscale experiments
    • Tutorial: microfluidic bioreactors - microfluidics fundamentals, bioreactor design and application
    • Rapid fermentation process development: industrial perspective 

    Who the course is for

    This course is for:

    • fermentation scientists and engineers in biotechnology and biopharmaceutical companies involved in process transfer to manufacturers
    • those in established fermentation development groups who want to be kept up to date with the latest research in this area

      Learning outcomes

      After completing this course you should be able to:

      • understand the engineering principles of fermentation
      • determine power consumption and oxygen mass transfer
      • evaluate different strategies for scale-up and scale-down
      • understand miniaturised bioreactors and their role in fermentation process development
      • design a bioreactor and use data from microscale experiments for scale-up

      Costs and group bookings

      The standard price for this course is £1,750.

      Special prices are available for groups and SMEs. Contact mbi-training@ucl.ac.uk for more information.

      Modular Training for the Bioprocess Industries (MBI)

      The award-winning MBI programme is a series of UCL-accredited short courses for people working in the bioprocessing industry. It's designed and delivered in collaboration with over 70 industrial experts.

      The programme provides flexible professional development training. You can choose to take standalone courses or combine them for a Certificate, Diploma or Master's qualification. It complements in-house training by providing broader perspectives for more informed decision-making.

      Courses have so far been delivered to over 900 individuals from more than 300 companies, 30% of which are non-UK, demonstrating its strong international impact.

      MBI plays a central role in the department's knowledge-transfer activities. This ensures that cutting-edge research is undertaken to capture the value of integrating engineering with complex and fast-moving biology, which helps keep the global industry ahead in manufacturing.

      Benefits of MBI

      By attending an MBI course, you'll:

      • benefit from knowledge transfer and upskilling in core bioprocessing fundamentals and trends in industry
      • gain a deeper understanding of process options and engineering constraints
      • acquire the tools to optimise process performance and economics
      • learn about the latest technical and regulatory developments
      • have access to cutting edge research methodologies
      • network with sector leaders and subject matter experts
      • increase your flexibility, motivation, creativity and professional status

      Further information

      There is more information about the MBI on the Department of Biochemical Engineering's website. If you have questions about fees or how to combine courses for a specific qualification, please email mbi-training@ucl.ac.uk

      Course team

      Dr Frank Baganz - Module Leader

      Dr Frank Baganz - Module Leader

      Frank is a Senior Lecturer in the Department of Biochemical Engineering at UCL.

      Course information last modified: 25 Jan 2022, 11:42