A common theme is combating pathological polymers including those that lead to serpinopathies, such as antitrypsin deficiency.

We also seek to combat the pathological polymers that lead to neurodegenerative diseases, including Alzheimer's disease.

To this end and with the aim of expediting translation to the clinic, structural, molecular and cell-based studies are pursued, alongside work on animal models (C. elegans), together with target-based and phenotypic drug screening. 

Head of Centre

• Professor David Lomas

Principal Investigators

• Prof David Sattelle