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Centre for Respiratory Biology

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Centre for Respiratory Biology

The group focuses on understanding disease mechanisms and the search for novel therapies.

A common theme is combating pathological polymers including those which lead to serpinopathies, such as antitrypsin deficiency.

We also seek to combat the pathological polymers which lead to neurodegenerative diseases, including Alzheimer's disease.

To this end and with the aim of expediting translation to the clinic, structural, molecular and cell-based studies are pursued, alongside work on animal models (C. elegans), together with target-based and phenotypic drug screening. 

Head of Centre

Principal Investigators