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Ancient Gene mutation could protect against diabetes

4 June 2019

UCL researchers have found an ancient mutation that spread through humans after the advent of cooking may protect people against high blood sugar and diabetes today.

gene mutation could protect against diabetes

Researchers discovered the mutation while studying a gene called CLTCL1, which is heavily involved in removing sugar from the bloodstream. While a certain amount of blood sugar is necessary to provide energy to the brain and other organs, too much leads to type 2 diabetes, where the body loses its ability to control how much sugar is circulating. The scientists found that about half the world’s population carries a mutation that helps the body to clear sugar from the circulation more effectively than in the past. Read more in the Guardian