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Prof Simon Gaisford

Prof Simon Gaisford

Professor of Pharmaceutics

Pharmaceutics

UCL School of Pharmacy

Joined UCL
1st Apr 2003

Research summary

My research group uses 3D printing to engineer personalised medicines. We characterise printed products with thermal analysis and isothermal microcalorimetry.

We have pioneered the use of a number of 3D printing technologies for fabrication of medicines, including fused-deposition modelling (FDM) to make PrintletsTM, stereolithography (SLA) to make hydrogels and selective laser sintering (SLS) to make oro-fast dispersing tablets.

We have shown that the rapid evaporation rates of ink-jet printed droplets upon contact with a substrate favours crystallisation of metastable forms (Cryst. Eng. Comm. 15 (2013) 1031). In collaboration with Sally Price (UCL Chemistry) and Alastair Florence (Strathclyde) we have been awarded £1.24m by EPSRC (EP/K03929/1) for the project 'Computationally designed templates for exquisite control of polymorphic form' (www.cposs.org.uk).

Finally, we focus on effective formulation of probiotic bacteria and have a number of in-vitro models to test efficacy of oral delivery.  Our recent work on Probiotics has featured in the Daily Mail, Express, Times and Telegraph and we were asked to test fermented foodstuffs for the Channel 4 programme 'Food Unwrapped'.

Teaching summary

Professor Gaisford teaches in years 1-3 of the MPharm degree, delivering lectures on basic pharmaceutics. He also runs an MSc option (Preformulation), in which basic and advanced methods of physicochemical characterisation are introduced.

Professor Gaisford was Programme Director of the MSc in Drug Delivery from 2004-2013, a successful postgraduate course that provides transferable skills and knowledge to allow students to progress their careers in either the pharmaceutical industry or in academia. He is now Deputy Programme Director of the MSc in Pharmaceutics and MSc in Pharmaceutical Formulation and Entrepreneurship. In 2013 took over as Head of the Department of Pharmaceutics.

Professor Gaisford also teaches on MSc courses at King's College London, the University of Manchester and the University of Bradford and acts as External Examiner for Cardiff University (MPharm) and Brighton University (MSc).

He recently published his first undergraduate textbook,  Essentials of Pharmaceutical Preformulation (www.wiley.com/buy/978-0-470-97636-4) and has a chapter in the successful undergraduate text, Aulton's Pharmaceutics.

Biography

Professor Gaisford has a Chair in Pharmaceutics and is Head of the Department of Pharmaceutics. He joined the School in 2003, having previously been a Lecturer in Pharmaceutical Science at the University of Huddersfield. He undertook his PhD at the University of Kent at Canterbury, under Professor AE Beezer and then held Postdoctoral Research Assistant posts at the School with Profs DQM Craig and G Buckton. Prof Gaisford is an Honorary Teaching Fellow at the University of Manchester and Past Chair of the Thermal Methods Group (Royal Society of Chemistry). He has published 137 papers, 8 book chapters and 4 books and received the 2006 Stig Sunner award from the US Calorimetry Conference.

Publications